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> Protein (NX_A0AVI4)
Protein (NX_A0AVI4)
Protein
Gene SymbolTMEM129 to neXtProt (NX_A0AVI4)
DescriptionE3 ubiquitin-protein ligase TM129
Chromosome4
Location4p16.3 (1717679 ~ 1723085) to Ensembl
Sequene Features : Isoforms 2, Variants 24, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein ubiquitination
.response to unfolded protein
.metal ion binding
.ligase activity
.integral component of membrane
.endoplasmic reticulum membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 24 0
2014-09-19protein level
2 18 0
2014-05-27protein level
2 18 1
2014-02-25protein level
2 18 1
2013-12-09protein level
2 12 1
2013-11-01protein level
2 12 1
2013-09-12protein level
2 12 1
2013-08-17protein level
2 12 1
2013-07-15transcript level
2 10 1
2013-06-11transcript level
2 10 1
2013-02-12transcript level
2 9 1
2012-12-20transcript level
2 10 1
2012-10-30transcript level
2 13 1
2012-10-07transcript level
2 13 1
2012-08-24transcript level
2 13 1
2012-07-28transcript level
2 13 1
2012-06-08transcript level
2 13 1
2012-05-07transcript level
2 13 1
2012-04-10transcript level
2 13 1
2012-01-13transcript level
2 7 1
2011-12-20transcript level
2 7 1
2011-11-11transcript level
2 7 1
2011-08-23transcript level
2 7 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_A0AVI4-1
5 10 0 40437.3166
NX_A0AVI4-2
1 10 0 25897.3149
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland60
ascites50
bone41
brain72
cervix82
connective tissue20
ear124
embryonic tissue42
eye33
intestine38
kidney66
liver14
lung38
lymph22
lymph node55
mammary gland33
mouth15
nerve128
ovary78
pancreas37
pituitary gland60
placenta28
prostate116
salivary gland148
skin61
stomach83
testis18
thyroid42
tonsil117
trachea38
uterus25
vascular19
Health State
TissuesTPM*
normal35
adrenal tumor158
breast (mammary gland) tumor53
chondrosarcoma36
colorectal tumor35
gastrointestinal tumor92
germ cell tumor26
glioma111
head and neck tumor44
kidney tumor58
leukemia21
liver tumor31
lung tumor9
lymphoma27
ovarian tumor78
pancreatic tumor47
primitive neuroectodermal tumor of the CNS133
prostate cancer115
skin tumor87
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult35
embryoid body71
blastocyst48
fetus28
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17.4
adrenal gland18.1
appendix13
bone marrow5.5
cerebral cortex14
colon17.2
duodenum20.4
esophagus13.9
gallbladder13.8
heart muscle22.5
kidney24.4
liver10.3
lung17.6
lymph node14.5
ovary18
pancreas16.7
placenta12
prostate19.4
salivary gland25
skin14.7
small intestine16.6
spleen19.1
stomach16
testis11.8
thyroid gland21.6
urinary bladder14.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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