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> Protein (NX_A0AVT1)
Protein (NX_A0AVT1)
Protein
Gene SymbolUBA6 to neXtProt (NX_A0AVT1)
DescriptionUbiquitin-like modifier-activating enzyme 6
Chromosome4
Location4q13.2 (68478370 ~ 68566897) to Ensembl
Sequene Features : Isoforms 4, Variants 110, PTMs 12 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein ubiquitination
.ubiquitin-dependent protein catabolic process
.FAT10 activating enzyme activity
.ATP binding
.cytosol
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 110 12
2014-09-19protein level
4 94 12
2014-05-27protein level
4 94 12
2014-02-25protein level
4 94 11
2013-12-09protein level
4 74 11
2013-11-01protein level
4 71 5
2013-09-12protein level
4 71 5
2013-08-17protein level
4 71 5
2013-07-15protein level
4 46 2
2013-06-11protein level
4 46 2
2013-02-12protein level
4 18 7
2012-12-20protein level
4 18 7
2012-10-30protein level
4 22 7
2012-10-07protein level
4 22 3
2012-08-24protein level
4 16 3
2012-07-28protein level
4 16 3
2012-06-08protein level
4 29 3
2012-05-07protein level
4 29 3
2012-04-10protein level
4 29 3
2012-01-13protein level
4 20 3
2011-12-20protein level
4 20 3
2011-11-11protein level
4 20 2
2011-08-23protein level
4 20 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_A0AVT1-1
4 53 0 117894.7243
NX_A0AVT1-2
0 36 0 65714.7968
NX_A0AVT1-3
2 17 0 43188.4635
NX_A0AVT1-4
2 15 0 37668.6795
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5282516,EBI-2549423 HMBOX1  
  .positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .cytoplasm
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder133
blood16
bone13
bone marrow61
brain34
cervix123
connective tissue6
ear62
embryonic tissue70
eye28
heart11
intestine25
kidney33
larynx42
liver19
lung50
lymph node100
mammary gland33
mouth45
muscle84
nerve128
ovary88
pancreas60
pharynx24
placenta21
prostate10
salivary gland49
skin23
spleen18
stomach20
testis27
thymus50
thyroid21
trachea57
uterus51
Health State
TissuesTPM*
normal35
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor32
cervical tumor57
chondrosarcoma12
colorectal tumor44
gastrointestinal tumor16
germ cell tumor37
head and neck tumor44
kidney tumor72
leukemia42
liver tumor20
lung tumor9
lymphoma13
non-neoplasia51
ovarian tumor118
pancreatic tumor76
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor23
soft tissue/muscle tissue tumor31
uterine tumor22
Developmental Stage
TissuesTPM*
adult47
embryoid body114
blastocyst65
fetus32
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.5
adrenal gland9.4
appendix13.7
bone marrow9.2
cerebral cortex12.8
colon12.4
duodenum9.8
esophagus18.5
gallbladder12.8
heart muscle6.8
kidney9.7
liver10.3
lung10.3
lymph node15.9
ovary10.7
pancreas3.8
placenta13.8
prostate9.9
salivary gland5.2
skin7.7
small intestine10.2
spleen13.6
stomach17.3
testis15.3
thyroid gland11.8
urinary bladder17
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611361, gene) Ubiquitin-activating enzyme e1-like 2; UBE1L2OMIM


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