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> Protein (NX_A1A4S6)
Protein (NX_A1A4S6)
Protein
Gene SymbolARHGAP10 to neXtProt (NX_A1A4S6)
DescriptionRho GTPase-activating protein 10
Chromosome4
Location4q31.23 (148653214 ~ 148993931) to Ensembl
Sequene Features : Isoforms 1, Variants 115, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of small GTPase mediated signal transduction
.negative regulation of apoptotic process
.regulation of apoptotic process
  + 4 more...
.GTPase activator activity .perinuclear region of cytoplasm
.plasma membrane
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 115 0
2014-09-19protein level
1 93 0
2014-05-27protein level
1 92 0
2014-02-25protein level
1 93 0
2013-12-09protein level
1 76 0
2013-11-01protein level
1 73 0
2013-09-12protein level
1 73 2
2013-08-17protein level
1 73 2
2013-07-15protein level
1 52 2
2013-06-11protein level
1 52 2
2013-02-12protein level
1 32 2
2012-12-20protein level
1 30 2
2012-10-30protein level
1 34 2
2012-10-07protein level
1 34 2
2012-08-24protein level
1 31 2
2012-07-28protein level
1 31 2
2012-06-08protein level
1 33 2
2012-05-07protein level
1 29 2
2012-04-10protein level
1 29 2
2012-01-13protein level
1 14 2
2011-12-20protein level
1 14 2
2011-11-11protein level
1 14 2
2011-08-23protein level
1 14 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_A1A4S6-1
34 0 0 89318.0879
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1390944,EBI-1384335 PKN3  
  .epithelial cell migration
.signal transduction
.protein phosphorylation
.ATP binding
.protein kinase C activity
.protein kinase activity
.perinuclear region of cytoplasm
.Golgi apparatus
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
bone69
brain8
connective tissue13
embryonic tissue23
esophagus49
eye19
heart11
intestine21
kidney52
liver14
lung14
mammary gland13
mouth30
muscle28
nerve64
placenta14
prostate10
skin28
spleen18
stomach10
testis6
uterus8
vascular19
Health State
TissuesTPM*
normal14
breast (mammary gland) tumor21
chondrosarcoma60
colorectal tumor17
gastrointestinal tumor8
germ cell tumor11
glioma18
head and neck tumor14
kidney tumor116
liver tumor10
ovarian tumor26
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor23
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult12
embryoid body42
fetus7
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.5
adrenal gland12.4
appendix7.2
bone marrow2.7
cerebral cortex2.8
colon8.5
duodenum4.9
esophagus39.9
gallbladder17.1
heart muscle26.6
kidney9.2
liver13.2
lung9.1
lymph node6.7
ovary26
pancreas3.1
placenta10.3
prostate19.9
salivary gland3.3
skin10.6
small intestine4.7
spleen7.9
stomach7
testis11.2
thyroid gland8.7
urinary bladder23.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609746, gene) Rho gtpase-activating protein 10; ARHGAP10OMIM


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