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> Protein (NX_A2RU14)
Protein (NX_A2RU14)
Protein
Gene SymbolTMEM218 to neXtProt (NX_A2RU14)
DescriptionTransmembrane protein 218
Chromosome11
Location11q24.2 (124966398 ~ 124981659) to Ensembl
Sequene Features : Isoforms 1, Variants 16, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .integral component of membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 16 0
2014-09-19transcript level
1 12 0
2014-05-27transcript level
1 12 0
2014-02-25transcript level
1 12 0
2013-12-09transcript level
1 8 0
2013-11-01transcript level
1 8 0
2013-09-12transcript level
1 8 0
2013-08-17transcript level
1 8 0
2013-07-15transcript level
1 7 0
2013-06-11transcript level
1 7 0
2013-02-12transcript level
1 2 0
2012-12-20transcript level
1 2 0
2012-10-30transcript level
1 3 0
2012-10-07transcript level
1 3 0
2012-08-24transcript level
1 2 0
2012-07-28transcript level
1 2 0
2012-06-08transcript level
1 2 0
2012-05-07transcript level
1 2 0
2012-04-10transcript level
1 2 0
2012-01-13transcript level
1 0 0
2011-12-20transcript level
1 0 0
2011-11-11transcript level
1 0 0
2011-08-23transcript level
1 0 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_A2RU14-1
5 0 0 12450.9954
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10173151,EBI-358311 PCNA  
  .error-free translesion synthesis
.response to cadmium ion
.positive regulation of DNA replication
  + 24 more...
.DNA polymerase binding
.identical protein binding
.histone acetyltransferase binding
  + 7 more...
.PCNA-p21 complex
.extracellular exosome
.PCNA complex
  + 6 more...
2 EBI-10173151,EBI-10173166 LDLRAD1  
  .N/A .N/A .integral component of membrane
3 EBI-10173151,EBI-6942903 CREB3L1  
  .positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
.extracellular matrix constituent secretion
  + 3 more...
.transcription regulatory region DNA binding
.sequence-specific DNA binding
.cAMP response element binding
  + 2 more...
.integral component of membrane
.endoplasmic reticulum membrane
.endoplasmic reticulum
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland30
ascites25
blood32
bone13
brain8
cervix61
connective tissue6
embryonic tissue9
eye23
heart33
intestine8
kidney61
liver24
lung56
mammary gland19
muscle18
ovary39
pancreas37
placenta3
prostate26
skin42
testis6
thyroid21
trachea19
uterus30
Health State
TissuesTPM*
normal19
adrenal tumor79
breast (mammary gland) tumor21
cervical tumor28
chondrosarcoma12
colorectal tumor8
gastrointestinal tumor16
germ cell tumor22
glioma83
head and neck tumor14
kidney tumor72
leukemia42
liver tumor41
lung tumor9
lymphoma13
non-neoplasia10
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS15
prostate cancer19
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor22
Developmental Stage
TissuesTPM*
adult5
blastocyst32
fetus10
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue27.2
adrenal gland22.8
appendix18
bone marrow8.1
cerebral cortex9.6
colon17.4
duodenum15.2
esophagus14.5
gallbladder18.9
heart muscle9.5
kidney17.5
liver11.7
lung19.4
lymph node23
ovary18.6
pancreas8
placenta13.2
prostate20.8
salivary gland14.9
skin12.4
small intestine14.1
spleen20.1
stomach16.7
testis9.1
thyroid gland18
urinary bladder20.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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