|
| Protein |
|
| Gene Symbol | SMCO3 to neXtProt (NX_A2RU48) |
| Description | Single-pass membrane and coiled-coil domain-containing protein 3 |
| Chromosome | 12 |
| Location | 12p12.3 (14957584 ~ 14967116) to Ensembl |
|
|
Sequene Features : Isoforms 1, Variants 13, PTMs 0 to neXtProt Sequence Features
|
|
Gene
Ontologies |
| GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
.N/A |
.N/A |
.integral component of membrane |
|
|
| |
|
| Proteomic Evidences |
|
| |
|
| Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
|
| 2015-01-01 | | protein level | | | | | | | 1 |
| 13 |
| 0 |
|
| 2014-09-19 | | protein level | | | | | | | 1 |
| 20 |
| 0 |
|
| 2014-05-27 | | protein level | | | | | | | 1 |
| 20 |
| 0 |
|
| 2014-02-25 | | protein level | | | | | | | 1 |
| 20 |
| 0 |
|
| 2013-12-09 | | protein level | | | | | | | 1 |
| 11 |
| 0 |
|
| 2013-11-01 | | protein level | | | | | | | 1 |
| 10 |
| 0 |
|
| 2013-09-12 | | protein level | | | | | | | 1 |
| 10 |
| 0 |
|
| 2013-08-17 | | protein level | | | | | | | 1 |
| 10 |
| 0 |
|
| 2013-07-15 | | transcript level | | | | | | | 1 |
| 8 |
| 0 |
|
| 2013-06-11 | | transcript level | | | | | | | 1 |
| 8 |
| 0 |
|
| 2013-02-12 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
| 2012-12-20 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
| 2012-10-30 | | transcript level | | | | | | | 1 |
| 8 |
| 0 |
|
| 2012-10-07 | | transcript level | | | | | | | 1 |
| 8 |
| 0 |
|
| 2012-08-24 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
|
| 2012-07-28 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
|
| 2012-06-08 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
|
| 2012-05-07 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
|
| 2012-04-10 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
|
| 2012-01-13 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
| 2011-12-20 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
| 2011-11-11 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
| 2011-08-23 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
|
| |
|
| Protein Isoforms |
|
| |
| |
|
| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
|
|
| |
|
| Interacting Partners |
|
| |
|
| No. |
Exp. ref. |
Symbol |
|
PE |
Pr |
Ab |
Di |
|
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
| 1 |
EBI-10173195,EBI-713568 |
MAPK9 |
|
| | | | |
.positive regulation of apoptotic signaling pathway
.cellular response to growth factor stimulus
.cellular response to tumor necrosis factor
+ 45 more... |
.cysteine-type endopeptidase activator activity involved in apoptotic process
.transcription factor binding
.ATP binding
.JUN kinase activity |
.cytosol
.mitochondrion
.nucleoplasm |
|
| 2 |
EBI-10173195,EBI-739510 |
TRIM39 |
|
| | | | |
.positive regulation of apoptotic signaling pathway
.negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.protein ubiquitination
.apoptotic process |
.identical protein binding
.ligase activity
.zinc ion binding |
.cytosol
.mitochondrion |
|
|
| |
|
| EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
|
| |
|
| Body Sites | |
| Tissues | TPM* | |
|
| cervix | 20 | |
| connective tissue | 6 | |
| eye | 14 | |
| kidney | 14 | |
| prostate | 5 | |
|
| Health State | |
| Tissues | TPM* | |
|
| normal | 3 | |
| chondrosarcoma | 12 | |
|
| Developmental Stage | |
| Tissues | TPM* | |
|
| adult | 2 | |
| fetus | 7 | |
|
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
| |
|
| Expression level of Protein (ref. Human Protein Atlas) |
|
| |
|
| RNA-Seq. | |
| Tissues | FPKM | |
|
| gallbladder | 2.1 | |
| kidney | 2.8 | |
| lung | 1.2 | |
| spleen | 1.6 | |
|
| Cancer | |
| Tumor | Number of patients and Staining levels | |
| breast cancer | |
| carcinoid | |
| cervical cancer | |
| colorectal cancer | |
| endometrial cancer | |
| glioma | |
| head and neck cancer | |
| liver cancer | |
| lung cancer | |
| lymphoma | |
| melanoma | |
| ovarian cancer | |
| pancreatic cancer | |
| prostate cancer | |
| renal cancer | |
| skin cancer | |
| stomach cancer | |
| testis cancer | |
| thyroid cancer | |
| urothelial cancer | |
|
| RNA-seq colour codes |
|
|
Highly expressed RNAs (FPKM >50) | |
|
Moderately expressed RNAs (50> FPKM >10) | |
|
Lower expressed RNAs (10> FPKM >1) | |
|
The lowest expressed RNAs (FPKM value of 0 or 1) |
|
| Staining level colour codes |
|
|
Highly expressed protein | |
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Moderately expressed protein | |
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Lower expressed protein | |
|
Not Detected |
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> Protein (NX_A2RU48)