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Protein |
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Gene Symbol | SMCO3 to neXtProt (NX_A2RU48) |
Description | Single-pass membrane and coiled-coil domain-containing protein 3 |
Chromosome | 12 |
Location | 12p12.3 (14957584 ~ 14967116) to Ensembl |
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Sequene Features : Isoforms 1, Variants 13, PTMs 0 to neXtProt Sequence Features
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Gene Ontologies |
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
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.N/A |
.N/A |
.integral component of membrane |
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Proteomic Evidences |
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Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
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2015-01-01 | | protein level | | | | | | | 1 |
| 13 |
| 0 |
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2014-09-19 | | protein level | | | | | | | 1 |
| 20 |
| 0 |
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2014-05-27 | | protein level | | | | | | | 1 |
| 20 |
| 0 |
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2014-02-25 | | protein level | | | | | | | 1 |
| 20 |
| 0 |
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2013-12-09 | | protein level | | | | | | | 1 |
| 11 |
| 0 |
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2013-11-01 | | protein level | | | | | | | 1 |
| 10 |
| 0 |
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2013-09-12 | | protein level | | | | | | | 1 |
| 10 |
| 0 |
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2013-08-17 | | protein level | | | | | | | 1 |
| 10 |
| 0 |
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2013-07-15 | | transcript level | | | | | | | 1 |
| 8 |
| 0 |
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2013-06-11 | | transcript level | | | | | | | 1 |
| 8 |
| 0 |
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2013-02-12 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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2012-12-20 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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2012-10-30 | | transcript level | | | | | | | 1 |
| 8 |
| 0 |
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2012-10-07 | | transcript level | | | | | | | 1 |
| 8 |
| 0 |
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2012-08-24 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
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2012-07-28 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
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2012-06-08 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
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2012-05-07 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
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2012-04-10 | | transcript level | | | | | | | 1 |
| 7 |
| 0 |
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2012-01-13 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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2011-12-20 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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2011-11-11 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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2011-08-23 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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Protein Isoforms |
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| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
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Interacting Partners |
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No. |
Exp. ref. |
Symbol |
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PE |
Pr |
Ab |
Di |
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GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
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1 |
EBI-10173195,EBI-713568 |
MAPK9 |
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.positive regulation of apoptotic signaling pathway .cellular response to growth factor stimulus .cellular response to tumor necrosis factor + 45 more... |
.cysteine-type endopeptidase activator activity involved in apoptotic process .transcription factor binding .ATP binding .JUN kinase activity |
.cytosol .mitochondrion .nucleoplasm |
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2 |
EBI-10173195,EBI-739510 |
TRIM39 |
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.positive regulation of apoptotic signaling pathway .negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process .protein ubiquitination .apoptotic process |
.identical protein binding .ligase activity .zinc ion binding |
.cytosol .mitochondrion |
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EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
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Body Sites | |
Tissues | TPM* | |
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cervix | 20 | |
connective tissue | 6 | |
eye | 14 | |
kidney | 14 | |
prostate | 5 | |
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Health State | |
Tissues | TPM* | |
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normal | 3 | |
chondrosarcoma | 12 | |
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Developmental Stage | |
Tissues | TPM* | |
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adult | 2 | |
fetus | 7 | |
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TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
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Expression level of Protein (ref. Human Protein Atlas) |
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RNA-Seq. | |
Tissues | FPKM | |
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gallbladder | 2.1 | |
kidney | 2.8 | |
lung | 1.2 | |
spleen | 1.6 | |
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Cancer | |
Tumor | Number of patients and Staining levels | |
breast cancer | |
carcinoid | |
cervical cancer | |
colorectal cancer | |
endometrial cancer | |
glioma | |
head and neck cancer | |
liver cancer | |
lung cancer | |
lymphoma | |
melanoma | |
ovarian cancer | |
pancreatic cancer | |
prostate cancer | |
renal cancer | |
skin cancer | |
stomach cancer | |
testis cancer | |
thyroid cancer | |
urothelial cancer | |
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RNA-seq colour codes |
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Highly expressed RNAs (FPKM >50) |
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Moderately expressed RNAs (50> FPKM >10) |
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Lower expressed RNAs (10> FPKM >1) |
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The lowest expressed RNAs (FPKM value of 0 or 1) |
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Staining level colour codes |
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Highly expressed protein |
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Moderately expressed protein |
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Lower expressed protein |
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Not Detected |
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