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> Protein (NX_A4D1E9)
Protein (NX_A4D1E9)
Protein
Gene SymbolGTPBP10 to neXtProt (NX_A4D1E9)
DescriptionGTP-binding protein 10
Chromosome7
Location7q21.13 (89964537 ~ 90020769) to Ensembl
Sequene Features : Isoforms 3, Variants 52, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ribosome biogenesis .poly(A) RNA binding
.GTP binding
.GTPase activity
.magnesium ion binding
.mitochondrion
.nucleolus
.chromosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 52 1
2014-09-19protein level
3 41 1
2014-05-27protein level
3 40 1
2014-02-25protein level
3 40 1
2013-12-09protein level
3 34 1
2013-11-01protein level
3 32 0
2013-09-12protein level
3 32 0
2013-08-17protein level
3 32 0
2013-07-15protein level
3 21 0
2013-06-11protein level
3 21 0
2013-02-12protein level
3 14 0
2012-12-20protein level
3 14 0
2012-10-30protein level
3 19 0
2012-10-07protein level
3 19 0
2012-08-24protein level
3 19 0
2012-07-28protein level
3 19 0
2012-06-08protein level
3 20 0
2012-05-07protein level
3 18 0
2012-04-10protein level
3 18 0
2012-01-13protein level
3 11 0
2011-12-20protein level
3 11 0
2011-11-11protein level
3 11 0
2011-08-23protein level
3 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_A4D1E9-1
3 16 0 42905.497
NX_A4D1E9-2
0 15 0 34628.8401
NX_A4D1E9-3
1 5 0 12568.4614
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5453796,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
2 EBI-5453796,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
3 EBI-5453796,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood8
bone13
brain20
connective tissue6
embryonic tissue28
eye38
intestine34
kidney23
liver24
lung29
lymph22
lymph node66
mammary gland26
muscle28
ovary9
pancreas18
pharynx24
pituitary gland60
placenta10
prostate5
skin75
stomach31
testis16
thymus62
thyroid21
trachea38
uterus12
vascular19
Health State
TissuesTPM*
normal21
breast (mammary gland) tumor21
colorectal tumor44
gastrointestinal tumor33
germ cell tumor22
head and neck tumor7
liver tumor20
lung tumor9
lymphoma41
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS39
retinoblastoma43
skin tumor87
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult18
embryoid body71
blastocyst16
fetus16
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.1
adrenal gland10.1
appendix11.7
bone marrow5.9
cerebral cortex8.2
colon12
duodenum10.7
esophagus11.3
gallbladder9
heart muscle9.8
kidney14.7
liver10.4
lung7.7
lymph node13
ovary9.9
pancreas4.1
placenta7.8
prostate8.9
salivary gland7.3
skin7.2
small intestine8.9
spleen9.1
stomach12.5
testis15.4
thyroid gland12
urinary bladder9.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610920, gene) Gtp-binding protein 10; GTPBP10OMIM


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