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> Protein (NX_A4GXA9)
Protein (NX_A4GXA9)
Protein
Gene SymbolEME2 to neXtProt (NX_A4GXA9)
DescriptionProbable crossover junction endonuclease EME2
Chromosome16
Location16p13.3 (1823208 ~ 1831709) to Ensembl
Sequene Features : Isoforms 2, Variants 50, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.DNA recombination
.DNA repair
.endonuclease activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 50 0
2014-09-19protein level
2 45 0
2014-05-27protein level
2 45 0
2014-02-25protein level
2 36 0
2013-12-09protein level
2 19 0
2013-11-01protein level
2 18 0
2013-09-12protein level
2 18 0
2013-08-17protein level
2 18 0
2013-07-15protein level
2 16 0
2013-06-11protein level
2 16 0
2013-02-12protein level
2 13 0
2012-12-20protein level
2 13 0
2012-10-30protein level
2 13 0
2012-10-07protein level
2 13 0
2012-08-24protein level
2 13 0
2012-07-28protein level
2 16 0
2012-06-08protein level
2 16 0
2012-05-07protein level
2 13 0
2012-04-10protein level
2 13 0
2012-01-13protein level
2 0 0
2011-12-20protein level
2 4 0
2011-11-11protein level
2 4 0
2011-08-23protein level
2 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_A4GXA9-1
7 10 0 41152.1098
NX_A4GXA9-2
3 10 0 26429.4049
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain8
connective tissue6
embryonic tissue32
eye9
intestine4
kidney4
mouth15
nerve64
ovary9
pancreas14
placenta7
stomach20
testis4
uterus4
Health State
TissuesTPM*
normal9
gastrointestinal tumor8
germ cell tumor7
glioma9
head and neck tumor7
kidney tumor14
uterine tumor11
Developmental Stage
TissuesTPM*
adult6
embryoid body14
blastocyst81
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.6
adrenal gland6.5
appendix6.5
bone marrow5.8
cerebral cortex4.8
colon4.5
duodenum12.5
esophagus3.9
gallbladder4.6
heart muscle2.4
kidney4.5
liver1.1
lung5.7
lymph node6.6
ovary3
pancreas3.6
placenta3.4
prostate12
salivary gland6.9
skin7.3
small intestine6.8
spleen8.7
stomach8.8
testis6.9
thyroid gland3.7
urinary bladder3.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610886, gene) Essential meiotic endonuclease 1, s. pombe, homolog of, 2; EME2OMIM


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