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> Protein (NX_B5ME19)
Protein (NX_B5ME19)
Protein
Gene SymbolEIF3CL to neXtProt (NX_B5ME19)
DescriptionEukaryotic translation initiation factor 3 subunit C-like protein
Chromosome16
Location16p11.2 (28390900 ~ 28415200) to Ensembl
Sequene Features : Isoforms 1, Variants 4, PTMs 12 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of translational initiation
.formation of translation preinitiation complex
.translation initiation factor activity .eukaryotic 48S preinitiation complex
.eukaryotic 43S preinitiation complex
.eukaryotic translation initiation factor 3 complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 4 12
2014-09-19protein level
1 4 12
2014-02-25homology
1 4 21
2013-12-09transcript level
1 3 21
2013-11-01transcript level
1 2 20
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_B5ME19-1
1 0 38 105406.4625
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue699
adrenal gland91
ascites652
bladder66
blood229
bone349
bone marrow102
brain135
cervix556
connective tissue114
embryonic tissue220
esophagus49
eye368
heart368
intestine452
kidney204
larynx298
liver326
lung328
lymph406
lymph node178
mammary gland416
mouth196
muscle413
nerve64
ovary512
pancreas201
pituitary gland484
placenta215
prostate195
salivary gland49
skin559
spleen168
stomach397
testis167
thymus87
thyroid579
tonsil352
umbilical cord1453
uterus314
vascular19
Health State
TissuesTPM*
normal156
breast (mammary gland) tumor483
cervical tumor782
chondrosarcoma217
colorectal tumor666
esophageal tumor57
gastrointestinal tumor548
germ cell tumor334
glioma382
head and neck tumor343
kidney tumor304
leukemia296
liver tumor510
lung tumor651
lymphoma290
non-neoplasia134
ovarian tumor643
pancreatic tumor314
primitive neuroectodermal tumor of the CNS307
prostate cancer250
retinoblastoma732
skin tumor837
soft tissue/muscle tissue tumor367
uterine tumor510
Developmental Stage
TissuesTPM*
adult292
embryoid body142
blastocyst162
neonate96
fetus190
infant212
juvenile251
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue77
adrenal gland50.2
appendix51.9
bone marrow46.3
cerebral cortex53.3
colon82.8
duodenum64.6
esophagus69
gallbladder47
heart muscle55.6
kidney71.2
liver36.4
lung60.1
lymph node60.8
ovary103.2
pancreas52.9
placenta53.6
prostate54.9
salivary gland72.9
skin88.3
small intestine63.3
spleen56.8
stomach57.7
testis80.3
thyroid gland88.6
urinary bladder72.5
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowLow
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleLow
hippocampusHigh
kidneyHigh
lateral ventricleMedium
liverLow
lungMedium
lymph nodeHigh
nasopharynxHigh
oral mucosaHigh
ovaryMedium
pancreasHigh
parathyroid glandMedium
placentaMedium
prostateMedium
rectumHigh
salivary glandHigh
seminal vesicleMedium
skeletal muscleLow
skin 1Medium
skin 2High
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenHigh
stomach 1Medium
stomach 2High
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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