Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O00194)
Protein (NX_O00194)
Protein
Gene SymbolRAB27B to neXtProt (NX_O00194)
DescriptionRas-related protein Rab-27B
Chromosome18
Location18q21.2 (52385091 ~ 52562747) to Ensembl
Sequene Features : Isoforms 1, Variants 36, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.multivesicular body sorting pathway
.positive regulation of exocytosis
.Rab protein signal transduction
  + 5 more...
.myosin V binding
.protein domain specific binding
.GDP binding
  + 2 more...
.extracellular exosome
.zymogen granule membrane
.melanosome
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 36 5
2014-09-19protein level
1 25 5
2014-05-27protein level
1 25 5
2014-02-25protein level
1 23 5
2013-12-09protein level
1 16 5
2013-11-01protein level
1 14 5
2013-09-12protein level
1 14 5
2013-08-17protein level
1 14 5
2013-07-15protein level
1 10 5
2013-06-11protein level
1 10 5
2013-02-12protein level
1 6 5
2012-12-20protein level
1 7 5
2012-10-30protein level
1 11 5
2012-10-07protein level
1 11 5
2012-08-24protein level
1 10 5
2012-07-28protein level
1 10 5
2012-06-08protein level
1 10 5
2012-05-07protein level
1 9 5
2012-04-10protein level
1 9 5
2012-01-13protein level
1 3 5
2011-12-20protein level
1 3 5
2011-11-11protein level
1 3 5
2011-08-23protein level
1 3 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00194-1
9 0 2 24592.1605
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10179046,EBI-741925 DHPS  
  .protein homotetramerization
.deoxyhypusine biosynthetic process from spermidine
.cellular protein metabolic process
  + 6 more...
.deoxyhypusine synthase activity .cytosol
2 EBI-10179046,EBI-2939487 SYTL5  
  .calcium ion-dependent exocytosis of neurotransmitter
.regulation of calcium ion-dependent exocytosis
.synaptic vesicle exocytosis
  + 2 more...
.clathrin binding
.syntaxin binding
.calcium-dependent phospholipid binding
.calcium ion binding
.exocytic vesicle
.plasma membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood8
bone13
bone marrow20
brain20
connective tissue13
eye14
intestine12
kidney4
liver4
lung17
mammary gland39
mouth15
muscle65
nerve128
pancreas4
pituitary gland60
placenta7
prostate36
testis4
trachea173
uterus4
Health State
TissuesTPM*
normal15
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor26
gastrointestinal tumor8
glioma65
leukemia21
lung tumor19
non-neoplasia10
pancreatic tumor9
prostate cancer19
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult14
fetus12
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland2.6
appendix1.7
cerebral cortex14.8
colon5
duodenum4.7
esophagus15.7
gallbladder4.5
lung5
pancreas2.3
placenta1.3
prostate18.9
salivary gland10
skin12.8
small intestine5
spleen1.6
stomach38.6
testis3.3
urinary bladder9.8
Tissues
TissuesExpression level
adrenal glandLow
appendixLow
bone marrowMedium
breastMedium
cerebellumLow
cerebral cortexLow
colonHigh
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisLow
esophagusLow
gallbladderMedium
kidneyHigh
lungLow
lymph nodeLow
pancreasMedium
parathyroid glandLow
prostateHigh
rectumMedium
salivary glandHigh
seminal vesicleLow
skeletal muscleLow
small intestineMedium
smooth muscleLow
soft tissue 2Low
spleenHigh
stomach 1High
stomach 2High
testisLow
tonsilLow
urinary bladderHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603869, gene) Ras-associated protein rab27b; RAB27BOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center