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> Protein (NX_O00219)
Protein (NX_O00219)
Protein
Gene SymbolHAS3 to neXtProt (NX_O00219)
DescriptionHyaluronan synthase 3
Chromosome16
Location16q22.1 (69139467 ~ 69152622) to Ensembl
Sequene Features : Isoforms 2, Variants 55, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of hyaluranon cable assembly
.extracellular matrix assembly
.positive regulation of transcription, DNA-templated
  + 7 more...
.hyaluronan synthase activity .hyaluranon cable
.integral component of membrane
.integral component of plasma membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 55 1
2014-09-19protein level
2 44 1
2014-05-27protein level
2 44 1
2014-02-25protein level
2 44 1
2013-12-09protein level
2 39 1
2013-11-01protein level
2 38 1
2013-09-12protein level
2 38 1
2013-08-17protein level
2 38 1
2013-07-15protein level
2 28 1
2013-06-11protein level
2 28 1
2013-02-12protein level
2 12 1
2012-12-20protein level
2 12 1
2012-10-30protein level
2 14 1
2012-10-07protein level
2 14 1
2012-08-24protein level
2 14 1
2012-07-28protein level
2 14 1
2012-06-08protein level
2 15 1
2012-05-07protein level
2 14 1
2012-04-10protein level
2 14 1
2012-01-13protein level
2 4 1
2011-12-20protein level
2 4 1
2011-11-11protein level
2 4 1
2011-08-23protein level
1 4 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00219-1
13 9 3 62957.0613
NX_O00219-2
3 9 1 31179.6342
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
brain8
connective tissue6
embryonic tissue28
eye9
intestine17
kidney4
lung11
mouth45
ovary9
pancreas9
prostate10
testis9
thyroid42
Health State
TissuesTPM*
normal6
bladder carcinoma56
chondrosarcoma12
colorectal tumor17
germ cell tumor22
glioma9
head and neck tumor37
pancreatic tumor19
prostate cancer19
Developmental Stage
TissuesTPM*
adult6
blastocyst48
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
colon6.1
duodenum2.7
esophagus8.2
gallbladder5.2
lung19.8
ovary1
placenta3.3
prostate1.7
skin5.4
small intestine2
stomach15.4
testis2.1
thyroid gland4.9
urinary bladder34.6
Tissues
TissuesExpression level
kidneyMedium
testisLow
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602428, gene) Hyaluronan synthase 3; HAS3OMIM


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