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> Protein (NX_O00311)
Protein (NX_O00311)
Protein
Gene SymbolCDC7 to neXtProt (NX_O00311)
DescriptionCell division cycle 7-related protein kinase
Chromosome1
Location1p22.2 (91966408 ~ 91991321) to Ensembl
Sequene Features : Isoforms 1, Variants 79, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.cell cycle phase transition
.peptidyl-serine phosphorylation
  + 10 more...
.metal ion binding
.kinase activity
.ATP binding
  + 2 more...
.intercellular bridge
.microtubule cytoskeleton
.cytoplasm
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 79 2
2014-09-19protein level
1 71 2
2014-05-27protein level
1 71 2
2014-02-25protein level
1 70 2
2013-12-09protein level
1 57 2
2013-11-01protein level
1 55 2
2013-09-12protein level
1 55 2
2013-08-17protein level
1 55 2
2013-07-15protein level
1 36 1
2013-06-11protein level
1 36 1
2013-02-12protein level
1 25 5
2012-12-20protein level
1 25 5
2012-10-30protein level
1 25 5
2012-10-07protein level
1 25 5
2012-08-24protein level
1 25 5
2012-07-28protein level
1 25 5
2012-06-08protein level
1 27 5
2012-05-07protein level
1 19 5
2012-04-10protein level
1 19 5
2012-01-13protein level
1 16 5
2011-12-20protein level
1 16 5
2011-11-11protein level
1 16 5
2011-08-23protein level
1 16 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00311-1
30 0 0 63847.5011
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-374980,EBI-749378 MCMBP  
  .cell division
.mitotic nuclear division
.sister chromatid cohesion
.DNA-dependent DNA replication
.chromatin binding .plasma membrane
.cytoplasm
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
blood24
bone marrow61
brain36
connective tissue6
embryonic tissue108
eye9
heart22
intestine12
kidney14
liver9
lung11
lymph node77
mammary gland6
mouth15
placenta14
prostate5
skin14
testis48
thymus75
thyroid21
uterus25
Health State
TissuesTPM*
normal30
adrenal tumor79
breast (mammary gland) tumor10
chondrosarcoma12
gastrointestinal tumor33
germ cell tumor41
glioma9
head and neck tumor14
kidney tumor29
leukemia31
lung tumor19
lymphoma13
non-neoplasia31
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult16
embryoid body100
blastocyst130
fetus59
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.6
adrenal gland2.7
appendix6.7
bone marrow9
cerebral cortex4.6
colon3.2
duodenum2.8
esophagus2.2
gallbladder2
kidney1.5
liver1.1
lung2.7
lymph node9.2
placenta4.8
prostate1.3
skin4.4
small intestine3.9
spleen9.1
stomach2
testis17.7
thyroid gland1.2
urinary bladder3.4
Tissues
TissuesExpression level
appendixHigh
bone marrowLow
breastMedium
bronchusMedium
cerebral cortexLow
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Low
epididymisMedium
esophagusLow
fallopian tubeLow
gallbladderLow
kidneyLow
lateral ventricleLow
lungLow
lymph nodeHigh
nasopharynxLow
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandLow
placentaMedium
prostateLow
rectumHigh
seminal vesicleLow
skin 1Low
skin 2High
small intestineMedium
soft tissue 1Low
soft tissue 2Low
stomach 1High
stomach 2Medium
testisHigh
thyroid glandLow
tonsilHigh
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603311, gene) Cell division cycle 7, s. cerevisiae, homolog-like 1; CDC7L1OMIM


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