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> Protein (NX_O00411)
Protein (NX_O00411)
Protein
Gene SymbolPOLRMT to neXtProt (NX_O00411)
DescriptionDNA-directed RNA polymerase, mitochondrial
Chromosome19
Location19p13.3 (617223 ~ 633597) to Ensembl
Sequene Features : Isoforms 1, Variants 143, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.gene expression
.mitochondrion organization
.organelle organization
  + 2 more...
.poly(A) RNA binding
.DNA-directed RNA polymerase activity
.DNA binding
.mitochondrial nucleoid
.mitochondrial matrix
.mitochondrion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 143 2
2014-09-19protein level
1 113 2
2014-05-27protein level
1 113 2
2014-02-25protein level
1 113 2
2013-12-09protein level
1 84 2
2013-11-01protein level
1 83 0
2013-09-12protein level
1 83 0
2013-08-17protein level
1 83 0
2013-07-15protein level
1 59 0
2013-06-11protein level
1 59 0
2013-02-12protein level
1 38 1
2012-12-20protein level
1 36 1
2012-10-30protein level
1 39 1
2012-10-07protein level
1 39 1
2012-08-24protein level
1 39 1
2012-07-28protein level
1 39 1
2012-06-08protein level
1 41 1
2012-05-07protein level
1 40 1
2012-04-10protein level
1 40 1
2012-01-13protein level
1 23 1
2011-12-20protein level
1 23 1
2011-11-11protein level
1 23 1
2011-08-23protein level
1 23 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00411-1
58 0 0 138531.4768
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bone13
brain22
cervix20
connective tissue6
embryonic tissue75
eye62
heart22
intestine12
kidney52
liver4
lung23
lymph67
lymph node22
mammary gland39
muscle18
ovary78
pancreas14
parathyroid97
placenta24
prostate5
spleen37
stomach20
testis232
thyroid21
uterus17
Health State
TissuesTPM*
normal27
breast (mammary gland) tumor53
chondrosarcoma12
colorectal tumor8
gastrointestinal tumor25
germ cell tumor11
glioma37
kidney tumor72
leukemia10
lung tumor48
lymphoma69
non-neoplasia10
ovarian tumor52
primitive neuroectodermal tumor of the CNS23
retinoblastoma43
uterine tumor44
Developmental Stage
TissuesTPM*
adult21
embryoid body85
blastocyst81
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.9
adrenal gland12.9
appendix14.7
bone marrow7.4
cerebral cortex8.8
colon11.4
duodenum18.5
esophagus8.7
gallbladder8.9
heart muscle13.2
kidney19.7
liver9.2
lung14
lymph node15.2
ovary12.5
pancreas8.2
placenta8.2
prostate14.1
salivary gland12
skin20
small intestine16.5
spleen21.2
stomach13.9
testis31.9
thyroid gland9.4
urinary bladder8.9
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastHigh
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverMedium
lungHigh
lymph nodeHigh
nasopharynxMedium
oral mucosaHigh
ovaryMedium
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleHigh
skeletal muscleHigh
skin 1Medium
skin 2High
small intestineHigh
smooth muscleHigh
soft tissue 1Medium
soft tissue 2Low
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*601778, gene) Polymerase, rna, mitochondrial; POLRMTOMIM


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