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> Protein (NX_O00425)
Protein (NX_O00425)
Protein
Gene SymbolIGF2BP3 to neXtProt (NX_O00425)
DescriptionInsulin-like growth factor 2 mRNA-binding protein 3
Chromosome7
Location7p15.3 (23349828 ~ 23510086) to Ensembl
Sequene Features : Isoforms 2, Variants 63, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mRNA transport
.regulation of cytokine biosynthetic process
.negative regulation of translation
  + 3 more...
.mRNA 5'-UTR binding
.translation regulator activity
.poly(A) RNA binding
  + 3 more...
.cytosol
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 63 13
2014-09-19protein level
2 53 13
2014-05-27protein level
2 53 14
2014-02-25protein level
2 53 14
2013-12-09protein level
2 49 14
2013-11-01protein level
2 49 12
2013-09-12protein level
2 49 12
2013-08-17protein level
2 49 12
2013-07-15protein level
2 33 7
2013-06-11protein level
2 33 7
2013-02-12protein level
2 13 8
2012-12-20protein level
2 15 8
2012-10-30protein level
2 15 8
2012-10-07protein level
2 15 6
2012-08-24protein level
2 7 6
2012-07-28protein level
2 7 6
2012-06-08protein level
2 9 6
2012-05-07protein level
2 9 6
2012-04-10protein level
2 9 6
2012-01-13protein level
2 4 6
2011-12-20protein level
2 4 6
2011-11-11protein level
2 4 6
2011-08-23protein level
2 4 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00425-1
18 8 3 63665.3762
NX_O00425-2
1 8 1 21616.3991
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood16
bone marrow225
brain10
cervix61
connective tissue13
embryonic tissue225
eye19
heart33
intestine8
liver19
lung2
lymph203
lymph node44
mouth15
muscle18
ovary19
pancreas9
placenta98
prostate5
skin9
testis32
thymus12
umbilical cord145
uterus17
vascular77
Health State
TissuesTPM*
normal34
cervical tumor86
chondrosarcoma12
colorectal tumor17
germ cell tumor26
glioma27
head and neck tumor7
leukemia95
liver tumor20
lymphoma124
non-neoplasia10
ovarian tumor26
pancreatic tumor19
prostate cancer9
retinoblastoma43
soft tissue/muscle tissue tumor31
Developmental Stage
TissuesTPM*
adult20
embryoid body228
blastocyst309
neonate96
fetus28
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix1.3
esophagus2.4
lung1.1
lymph node4.1
placenta30.5
testis7.7
thyroid gland1
urinary bladder1.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608259, gene) Insulin-like growth factor 2 mrna-binding protein 3; IGF2BP3OMIM


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