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> Protein (NX_O00483)
Protein (NX_O00483)
Protein
Gene SymbolNDUFA4 to neXtProt (NX_O00483)
DescriptionCytochrome c oxidase subunit NDUFA4
Chromosome7
Location7p21.3 (10971578 ~ 10979883) to Ensembl
Sequene Features : Isoforms 1, Variants 15, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.hydrogen ion transmembrane transport
.small molecule metabolic process
.cellular metabolic process
  + 2 more...
.protein complex binding
.NADH dehydrogenase (ubiquinone) activity
.extracellular exosome
.mitochondrial respiratory chain complex IV
.mitochondrial respiratory chain complex I
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 15 5
2014-09-19protein level
1 11 5
2014-05-27protein level
1 11 5
2014-02-25protein level
1 11 5
2013-12-09protein level
1 8 5
2013-11-01protein level
1 7 2
2013-09-12protein level
1 7 2
2013-08-17protein level
1 7 2
2013-07-15protein level
1 6 2
2013-06-11protein level
1 6 2
2013-02-12protein level
1 2 2
2012-12-20protein level
1 3 2
2012-10-30protein level
1 3 2
2012-10-07protein level
1 3 2
2012-08-24protein level
1 3 2
2012-07-28protein level
1 3 2
2012-06-08protein level
1 3 2
2012-05-07protein level
1 3 2
2012-04-10protein level
1 3 2
2012-01-13protein level
1 4 2
2011-12-20protein level
1 4 2
2011-11-11protein level
1 4 2
2011-08-23protein level
1 4 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00483-1
5 0 0 9363.8837
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland364
ascites351
bladder234
blood163
bone83
bone marrow677
brain135
cervix41
connective tissue114
ear248
embryonic tissue173
esophagus148
eye287
heart1027
intestine107
kidney132
liver321
lung119
lymph45
lymph node22
mammary gland46
mouth15
muscle376
ovary39
pancreas84
parathyroid1116
pituitary gland121
placenta109
prostate379
salivary gland246
skin161
spleen37
stomach376
testis66
thymus37
thyroid64
tonsil58
trachea19
umbilical cord508
uterus133
vascular697
Health State
TissuesTPM*
normal200
adrenal tumor632
bladder carcinoma284
breast (mammary gland) tumor53
cervical tumor28
chondrosarcoma156
colorectal tumor79
esophageal tumor173
gastrointestinal tumor286
germ cell tumor83
glioma279
head and neck tumor14
kidney tumor246
leukemia232
liver tumor270
lung tumor77
lymphoma27
non-neoplasia51
ovarian tumor39
pancreatic tumor104
primitive neuroectodermal tumor of the CNS47
prostate cancer577
retinoblastoma43
skin tumor71
soft tissue/muscle tissue tumor79
uterine tumor55
Developmental Stage
TissuesTPM*
adult197
embryoid body171
blastocyst97
neonate225
fetus154
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue22.3
adrenal gland29.8
appendix25.1
bone marrow22.7
cerebral cortex30.9
colon21.3
duodenum29.3
esophagus19.1
gallbladder16.4
heart muscle78.6
kidney39.2
liver17.6
lung20
lymph node20.5
ovary18.9
pancreas11.3
placenta13.9
prostate30.4
salivary gland30.8
skin11.3
small intestine23.6
spleen19
stomach28.4
testis11.7
thyroid gland22.1
urinary bladder19.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#256000, phenotype) Leigh syndrome; LSOMIM
2(*603833, gene) Nadh-ubiquinone oxidoreductase 1 alpha subcomplex, 4; NDUFA4OMIM


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