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> Protein (NX_O00592)
Protein (NX_O00592)
Protein
Gene SymbolPODXL to neXtProt (NX_O00592)
DescriptionPodocalyxin
Chromosome7
Location7q32.3 (131185021 ~ 131242976) to Ensembl
Sequene Features : Isoforms 2, Variants 86, PTMs 53 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.epithelial tube formation
.glomerular visceral epithelial cell development
.leukocyte migration
  + 7 more...
.N/A .extracellular exosome
.membrane raft
.cell body
  + 10 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 86 53
2014-09-19protein level
2 69 53
2014-05-27protein level
2 68 53
2014-02-25protein level
2 69 53
2013-12-09protein level
2 54 54
2013-11-01protein level
2 49 53
2013-09-12protein level
2 49 53
2013-08-17protein level
2 49 52
2013-07-15protein level
2 38 9
2013-06-11protein level
2 38 9
2013-02-12protein level
2 28 18
2012-12-20protein level
2 27 18
2012-10-30protein level
2 30 18
2012-10-07protein level
2 30 9
2012-08-24protein level
2 23 9
2012-07-28protein level
2 22 9
2012-06-08protein level
2 24 9
2012-05-07protein level
2 24 9
2012-04-10protein level
2 24 9
2012-01-13protein level
2 13 9
2011-12-20protein level
2 13 9
2011-11-11protein level
2 13 7
2011-08-23protein level
2 13 7
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00592-1
1 22 0 58598.9257
NX_O00592-2
1 22 0 55351.2625
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6897823,EBI-297509 IQGAP1  
  .neuron projection extension
.glomerular visceral epithelial cell development
.positive regulation of protein serine/threonine kinase activity
  + 16 more...
.protein serine/threonine kinase activator activity
.protein phosphatase binding
.protein kinase binding
  + 5 more...
.extracellular exosome
.neuron projection
.cytoplasmic ribonucleoprotein granule
  + 15 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue310
blood16
bone167
brain43
cervix123
connective tissue33
ear124
embryonic tissue558
esophagus99
eye67
heart89
intestine112
kidney90
larynx170
liver38
lung107
mammary gland79
mouth45
muscle169
nerve64
ovary354
pancreas89
parathyroid48
pharynx49
pituitary gland60
placenta17
prostate10
salivary gland49
skin9
stomach52
testis75
thyroid21
trachea77
umbilical cord145
uterus193
vascular154
Health State
TissuesTPM*
normal85
breast (mammary gland) tumor96
cervical tumor144
chondrosarcoma132
colorectal tumor151
esophageal tumor115
gastrointestinal tumor42
germ cell tumor227
glioma121
head and neck tumor52
kidney tumor58
leukemia21
liver tumor72
lung tumor19
non-neoplasia51
ovarian tumor144
pancreatic tumor47
primitive neuroectodermal tumor of the CNS7
prostate cancer19
soft tissue/muscle tissue tumor23
uterine tumor388
Developmental Stage
TissuesTPM*
adult93
embryoid body443
blastocyst1236
neonate64
fetus64
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue28.1
adrenal gland11.7
appendix14.2
cerebral cortex19
colon12.4
duodenum7.7
esophagus12.5
gallbladder27.9
heart muscle36.2
kidney120.5
liver2.5
lung49.6
lymph node8.5
ovary9.9
pancreas20.8
placenta22
prostate13.2
salivary gland20.3
skin6.9
small intestine10
spleen10.2
stomach8.3
testis4.8
thyroid gland44.3
urinary bladder19.7
Tissues
TissuesExpression level
breastLow
cerebral cortexHigh
colonMedium
endometrium 1Medium
endometrium 2Medium
fallopian tubeHigh
kidneyHigh
placentaLow
seminal vesicleMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602632, gene) Podocalyxin-like; PODXLOMIM


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