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> Protein (NX_O00631)
Protein (NX_O00631)
Protein
Gene SymbolSLN to neXtProt (NX_O00631)
DescriptionSarcolipin
Chromosome11
Location11q22.3 (107578104 ~ 107590419) to Ensembl
Sequene Features : Isoforms 1, Variants 4, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of calcium-transporting ATPase activity
.positive regulation of protein depolymerization
.negative regulation of calcium ion binding
  + 8 more...
.ATPase binding
.enzyme inhibitor activity
.sarcoplasmic reticulum membrane
.sarcoplasmic reticulum
.integral component of membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 4 0
2014-09-19protein level
1 4 0
2014-05-27protein level
1 4 0
2014-02-25protein level
1 4 0
2013-12-09protein level
1 3 0
2013-11-01protein level
1 2 0
2013-09-12protein level
1 2 0
2013-08-17protein level
1 2 0
2013-07-15protein level
1 2 0
2013-06-11protein level
1 2 0
2013-02-12protein level
1 1 0
2012-12-20protein level
1 1 0
2012-10-30protein level
1 1 0
2012-10-07protein level
1 1 0
2012-08-24protein level
1 0 0
2012-07-28protein level
1 0 0
2012-06-08protein level
1 2 0
2012-05-07protein level
1 2 0
2012-04-10protein level
1 2 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00631-1
1 0 0 3759.0553
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10180786,EBI-7131783 SYNE4  
  .establishment of epithelial cell apical/basal polarity .N/A .LINC complex
.integral component of nuclear outer membrane
2 EBI-10180786,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
3 EBI-10180786,EBI-8649725 TMEM79  
  .cornification
.establishment of skin barrier
.positive regulation of epidermis development
  + 4 more...
.N/A .trans-Golgi network membrane
.integral component of membrane
.lysosomal membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain2
connective tissue268
embryonic tissue9
eye19
heart223
intestine4
liver24
mammary gland6
mouth75
muscle676
nerve64
pancreas51
placenta3
prostate15
thyroid21
uterus4
Health State
TissuesTPM*
normal33
breast (mammary gland) tumor10
glioma18
head and neck tumor37
soft tissue/muscle tissue tumor335
Developmental Stage
TissuesTPM*
adult62
fetus62
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2
adrenal gland8.2
cerebral cortex10.1
colon1.2
esophagus128.3
heart muscle172.3
placenta1.1
prostate52.6
skin1.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602203, gene) Sarcolipin; SLNOMIM


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