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> Protein (NX_O00748)
Protein (NX_O00748)
Protein
Gene SymbolCES2 to neXtProt (NX_O00748)
DescriptionCocaine esterase
Chromosome16
Location16q22.1 (66968347 ~ 66978999) to Ensembl
Sequene Features : Isoforms 2, Variants 62, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.catabolic process .carboxylic ester hydrolase activity
.methylumbelliferyl-acetate deacetylase activity
.endoplasmic reticulum lumen
.endoplasmic reticulum
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 62 5
2014-09-19protein level
2 48 5
2014-05-27protein level
2 48 5
2014-02-25protein level
2 45 5
2013-12-09protein level
2 27 5
2013-11-01protein level
2 24 5
2013-09-12protein level
2 24 5
2013-08-17protein level
2 24 5
2013-07-15protein level
2 19 5
2013-06-11protein level
2 19 5
2013-02-12protein level
2 14 10
2012-12-20protein level
2 13 10
2012-10-30protein level
2 18 10
2012-10-07protein level
2 18 5
2012-08-24protein level
2 18 5
2012-07-28protein level
2 18 5
2012-06-08protein level
2 21 5
2012-05-07protein level
2 18 5
2012-04-10protein level
2 18 5
2012-01-13protein level
2 9 5
2011-12-20protein level
2 9 5
2011-11-11protein level
2 9 5
2011-08-23protein level
2 9 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O00748-1
2 21 0 61767.053
NX_O00748-2
0 21 0 59920.1899
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland121
ascites75
bladder66
blood16
bone13
brain92
cervix20
connective tissue67
embryonic tissue51
eye52
heart33
intestine340
kidney175
larynx42
liver126
lung77
lymph22
lymph node11
mammary gland99
mouth90
muscle9
nerve128
ovary78
pancreas32
placenta31
prostate63
salivary gland197
skin61
spleen93
stomach104
testis94
thymus50
thyroid42
trachea96
uterus56
vascular58
Health State
TissuesTPM*
normal73
adrenal tumor79
breast (mammary gland) tumor85
cervical tumor28
chondrosarcoma48
colorectal tumor142
gastrointestinal tumor118
germ cell tumor94
glioma37
head and neck tumor74
kidney tumor101
liver tumor145
lung tumor77
lymphoma13
non-neoplasia51
ovarian tumor91
pancreatic tumor57
primitive neuroectodermal tumor of the CNS55
prostate cancer48
retinoblastoma43
skin tumor71
soft tissue/muscle tissue tumor23
uterine tumor88
Developmental Stage
TissuesTPM*
adult65
embryoid body100
neonate32
fetus53
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.6
adrenal gland26
appendix19.4
bone marrow4.8
cerebral cortex16.9
colon132.1
duodenum379.7
esophagus91.3
gallbladder19.8
heart muscle25.7
kidney70.7
liver134.7
lung18.8
lymph node12.4
ovary18.6
pancreas8.1
placenta10.7
prostate19.5
salivary gland12.9
skin24.7
small intestine317.9
spleen14.8
stomach37.8
testis14.1
thyroid gland30.8
urinary bladder14.5
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisMedium
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverHigh
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaMedium
ovaryHigh
pancreasMedium
parathyroid glandHigh
placentaHigh
prostateMedium
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleHigh
skin 1High
skin 2High
small intestineHigh
smooth muscleHigh
soft tissue 1High
soft tissue 2High
spleenHigh
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605278, gene) Carboxylesterase 2; CES2OMIM


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