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> Protein (NX_O14558)
Protein (NX_O14558)
Protein
Gene SymbolHSPB6 to neXtProt (NX_O14558)
DescriptionHeat shock protein beta-6
Chromosome19
Location19q13.12 (36245469 ~ 36248980) to Ensembl
Sequene Features : Isoforms 1, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of muscle contraction .protein homodimerization activity
.structural constituent of eye lens
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 8 2
2014-09-19protein level
1 6 2
2014-05-27protein level
1 6 2
2014-02-25protein level
1 6 2
2013-12-09protein level
1 3 2
2013-11-01protein level
1 3 2
2013-09-12protein level
1 3 2
2013-08-17protein level
1 3 2
2013-07-15protein level
1 3 2
2013-06-11protein level
1 3 2
2013-02-12protein level
1 2 1
2012-12-20protein level
1 2 1
2012-10-30protein level
1 2 1
2012-10-07protein level
1 2 1
2012-08-24protein level
1 2 1
2012-07-28protein level
1 2 1
2012-06-08protein level
1 4 1
2012-05-07protein level
1 4 1
2012-04-10protein level
1 4 1
2012-01-13protein level
1 5 1
2011-12-20protein level
1 5 1
2011-11-11protein level
1 5 1
2011-08-23protein level
1 5 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14558-1
8 0 0 17124.9289
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739095,EBI-739074 HSPB8  
  .N/A .identical protein binding .Golgi apparatus
.cytoplasm
.nucleoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue466
adrenal gland30
bone13
bone marrow41
brain17
connective tissue13
embryonic tissue4
eye28
heart55
intestine21
mammary gland19
muscle84
ovary19
pancreas46
placenta14
prostate5
stomach20
testis4
uterus12
Health State
TissuesTPM*
normal74
breast (mammary gland) tumor10
chondrosarcoma48
gastrointestinal tumor8
glioma18
head and neck tumor29
lung tumor48
non-neoplasia10
pancreatic tumor19
skin tumor7
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult63
fetus12
infant85
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue394
adrenal gland148.6
appendix33.5
cerebral cortex10.1
colon67.9
duodenum19.7
esophagus80.6
gallbladder87.6
heart muscle377
kidney10
liver12
lung28.5
lymph node4.8
ovary124.7
pancreas11.9
placenta35
prostate179.9
salivary gland11.4
skin2.4
small intestine26.1
spleen4.7
stomach12.1
testis31.3
thyroid gland4.5
urinary bladder119.7
Tissues
TissuesExpression level
adrenal glandHigh
breastMedium
colonLow
endometrium 1High
heart muscleHigh
ovaryMedium
placentaHigh
skeletal muscleHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2High
testisHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610695, gene) Heat-shock 27-kd protein 6; HSPB6OMIM


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