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> Protein (NX_O14576)
Protein (NX_O14576)
Protein
Gene SymbolDYNC1I1 to neXtProt (NX_O14576)
DescriptionCytoplasmic dynein 1 intermediate chain 1
Chromosome7
Location7q21.3 (95401866 ~ 95739634) to Ensembl
Sequene Features : Isoforms 5, Variants 112, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.vesicle transport along microtubule
.antigen processing and presentation of exogenous peptide antigen via MHC class II
.metabolic process
.spectrin binding
.microtubule binding
.microtubule motor activity
.motor activity
.recycling endosome
.perinuclear region of cytoplasm
.cytoplasmic ribonucleoprotein granule
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 112 1
2014-09-19protein level
5 85 1
2014-05-27protein level
5 85 1
2014-02-25protein level
3 86 1
2013-12-09protein level
3 77 1
2013-11-01protein level
3 71 1
2013-09-12protein level
3 71 1
2013-08-17protein level
3 71 1
2013-07-15protein level
3 49 1
2013-06-11protein level
3 49 1
2013-02-12protein level
3 22 3
2012-12-20protein level
3 21 3
2012-10-30protein level
3 25 3
2012-10-07protein level
3 25 1
2012-08-24protein level
3 24 1
2012-07-28protein level
3 24 1
2012-06-08protein level
3 25 1
2012-05-07protein level
3 13 1
2012-04-10protein level
3 13 1
2012-01-13protein level
3 15 1
2011-12-20protein level
3 15 1
2011-11-11protein level
3 15 1
2011-08-23protein level
3 15 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14576-1
0 22 1 72909.4489
NX_O14576-2
0 22 1 70745.4304
NX_O14576-3
0 21 1 68532.3876
NX_O14576-4
1 19 1 67759.0897
NX_O14576-5
0 21 1 70696.4061
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bone marrow20
brain273
connective tissue13
ear248
embryonic tissue4
eye43
kidney56
mammary gland6
mouth45
nerve64
ovary9
pancreas18
prostate15
skin18
spleen18
testis6
thymus25
uterus12
Health State
TissuesTPM*
normal96
breast (mammary gland) tumor10
chondrosarcoma12
germ cell tumor30
head and neck tumor22
kidney tumor159
leukemia10
non-neoplasia31
skin tumor23
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult14
blastocyst16
fetus238
infant85
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.8
adrenal gland15.6
appendix2.2
cerebral cortex60.7
colon2.3
esophagus4.5
gallbladder3.2
heart muscle19.7
kidney2
lung1.2
ovary9.9
pancreas1.3
prostate7.5
skin1.3
small intestine1.5
stomach1.3
testis2.4
thyroid gland3
urinary bladder6.1
Tissues
TissuesExpression level
appendixLow
bronchusLow
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonHigh
epididymisMedium
esophagusLow
fallopian tubeMedium
gallbladderMedium
hippocampusMedium
kidneyMedium
nasopharynxMedium
oral mucosaLow
pancreasMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Low
stomach 1Low
stomach 2Medium
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603772, gene) Dynein, cytoplasmic 1, intermediate chain 1; DYNC1I1OMIM


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