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> Protein (NX_O14593)
Protein (NX_O14593)
Protein
Gene SymbolRFXANK to neXtProt (NX_O14593)
DescriptionDNA-binding protein RFXANK
Chromosome19
Location19p13.11 (19303008 ~ 19312678) to Ensembl
Sequene Features : Isoforms 3, Variants 42, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of transcription from RNA polymerase II promoter
.Ras protein signal transduction
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
.DNA binding
.intercellular bridge
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 42 3
2014-09-19protein level
3 32 3
2014-05-27protein level
3 32 3
2014-02-25protein level
2 32 3
2013-12-09protein level
2 29 3
2013-11-01protein level
2 28 3
2013-09-12protein level
2 28 3
2013-08-17protein level
2 28 3
2013-07-15protein level
2 21 0
2013-06-11protein level
2 21 0
2013-02-12protein level
2 13 0
2012-12-20protein level
2 13 0
2012-10-30protein level
2 11 0
2012-10-07protein level
2 11 0
2012-08-24protein level
2 10 0
2012-07-28protein level
2 10 0
2012-06-08protein level
2 10 0
2012-05-07protein level
2 9 0
2012-04-10protein level
2 9 0
2012-01-13protein level
2 7 0
2011-12-20protein level
2 7 0
2011-11-11protein level
2 7 0
2011-08-23protein level
2 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14593-1
2 10 0 28085.0613
NX_O14593-2
2 9 0 24228.0114
NX_O14593-3
0 11 0 25635.6957
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
ascites75
bladder66
blood57
bone41
brain31
cervix82
connective tissue33
embryonic tissue9
eye67
intestine38
kidney28
liver19
lung71
lymph790
lymph node233
mammary gland26
mouth15
muscle18
nerve64
ovary49
pancreas51
parathyroid145
placenta42
prostate26
skin23
spleen74
stomach10
testis18
thymus100
thyroid42
tonsil352
uterus12
Health State
TissuesTPM*
normal37
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor21
cervical tumor173
chondrosarcoma108
colorectal tumor17
gastrointestinal tumor42
germ cell tumor37
glioma83
head and neck tumor52
kidney tumor87
leukemia63
liver tumor41
lung tumor116
lymphoma249
non-neoplasia62
ovarian tumor39
pancreatic tumor57
primitive neuroectodermal tumor of the CNS15
prostate cancer19
skin tumor39
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult53
embryoid body71
blastocyst146
fetus53
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue26.9
adrenal gland18.2
appendix35.7
bone marrow42.8
cerebral cortex17.6
colon29
duodenum29.2
esophagus30.7
gallbladder24.2
heart muscle26.8
kidney30.4
liver9.8
lung32.8
lymph node44.3
ovary33
pancreas13.6
placenta29.8
prostate31.5
salivary gland38.9
skin35.1
small intestine26.1
spleen38.7
stomach29.2
testis12.6
thyroid gland43.2
urinary bladder33.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#209920, phenotype) Bare lymphocyte syndrome, type iiOMIM
2(*603200, gene) Regulatory factor x, ankyrin repeat-containing; RFXANKOMIM


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