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> Protein (NX_O14625)
Protein (NX_O14625)
Protein
Gene SymbolCXCL11 to neXtProt (NX_O14625)
DescriptionC-X-C motif chemokine 11
Chromosome4
Location4q21.1 (76954835 ~ 76962568) to Ensembl
Sequene Features : Isoforms 1, Variants 13, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.chemokine-mediated signaling pathway
.positive regulation of release of sequestered calcium ion into cytosol
.positive regulation of cAMP-mediated signaling
  + 11 more...
.CXCR3 chemokine receptor binding
.heparin binding
.chemokine activity
.extracellular space
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 13 3
2014-09-19protein level
1 11 3
2014-05-27protein level
1 11 3
2014-02-25protein level
1 11 3
2013-12-09protein level
1 9 3
2013-11-01protein level
1 8 3
2013-09-12protein level
1 8 3
2013-08-17protein level
1 8 3
2013-07-15protein level
1 6 3
2013-06-11protein level
1 6 3
2013-02-12protein level
1 5 3
2012-12-20protein level
1 5 3
2012-10-30protein level
1 5 3
2012-10-07protein level
1 5 3
2012-08-24protein level
1 1 3
2012-07-28protein level
1 1 3
2012-06-08protein level
1 4 3
2012-05-07protein level
1 6 3
2012-04-10protein level
1 6 3
2012-01-13protein level
1 4 3
2011-12-20protein level
1 4 3
2011-11-11protein level
1 4 3
2011-08-23protein level
1 4 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14625-1
4 0 0 10357.6319
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2871971,EBI-2871277 DPP4  
  .viral entry into host cell
.endothelial cell migration
.T cell activation
  + 5 more...
.protein homodimerization activity
.identical protein binding
.dipeptidyl-peptidase activity
  + 5 more...
.invadopodium membrane
.extracellular exosome
.intercellular canaliculus
  + 11 more...
2 EBI-2871971,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone marrow41
connective tissue6
intestine12
liver4
lung14
mammary gland19
mouth151
muscle9
salivary gland49
skin9
uterus17
vascular19
Health State
TissuesTPM*
normal3
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor17
head and neck tumor74
leukemia21
lymphoma13
skin tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult10
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.4
appendix11.1
colon2.1
gallbladder1.3
lung4.1
lymph node10
pancreas3.5
placenta2.9
prostate1.5
salivary gland2.2
small intestine1
spleen4
stomach7.1
testis1.3
thyroid gland1.2
urinary bladder3.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604852, gene) Chemokine, cxc motif, ligand 11; CXCL11OMIM


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