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> Protein (NX_O14627)
Protein (NX_O14627)
Protein
Gene SymbolCDX4 to neXtProt (NX_O14627)
DescriptionHomeobox protein CDX-4
ChromosomeX
LocationXq13.2 (72667090 ~ 72675081) to Ensembl
Sequene Features : Isoforms 1, Variants 55, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.labyrinthine layer development
.positive regulation of transcription from RNA polymerase II promoter
.anterior/posterior pattern specification
  + 2 more...
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 55 0
2014-09-19transcript level
1 37 0
2014-05-27transcript level
1 37 0
2014-02-25transcript level
1 37 0
2013-12-09transcript level
1 34 0
2013-11-01transcript level
1 30 0
2013-09-12transcript level
1 30 0
2013-08-17transcript level
1 30 0
2013-07-15transcript level
1 19 0
2013-06-11transcript level
1 19 0
2013-02-12transcript level
1 3 0
2012-12-20transcript level
1 3 0
2012-10-30transcript level
1 4 0
2012-10-07transcript level
1 4 0
2012-08-24transcript level
1 4 0
2012-07-28transcript level
1 4 0
2012-06-08transcript level
1 4 0
2012-05-07transcript level
1 4 0
2012-04-10transcript level
1 4 0
2012-01-13transcript level
1 0 0
2011-12-20transcript level
1 0 0
2011-11-11transcript level
1 0 0
2011-08-23transcript level
1 0 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14627-1
7 0 1 30460.7585
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10181162,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
2 EBI-10181162,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
3 EBI-10181162,EBI-8639312 LMO1  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.zinc ion binding .nucleus
4 EBI-10181162,EBI-456371 CKS1B  
  .cell division
.cell proliferation
.mitotic cell cycle
  + 2 more...
.cyclin-dependent protein serine/threonine kinase regulator activity .nucleoplasm
5 EBI-10181162,EBI-1181405 PRKAA1  
  .negative regulation of glucose import in response to insulin stimulus
.regulation of energy homeostasis
.response to camptothecin
  + 42 more...
.[acetyl-CoA carboxylase] kinase activity
.tau-protein kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
  + 7 more...
.AMP-activated protein kinase complex
.apical plasma membrane
.cytosol
  + 4 more...
Expression level of Protein (ref. Human Protein Atlas)
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300025, gene) Caudal-type homeobox transcription factor 4; CDX4OMIM


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