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> Protein (NX_O14645)
Protein (NX_O14645)
Protein
Gene SymbolDNALI1 to neXtProt (NX_O14645)
DescriptionAxonemal dynein light intermediate polypeptide 1
Chromosome1
Location1p34.3 (38022520 ~ 38032458) to Ensembl
Sequene Features : Isoforms 2, Variants 39, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.metabolic process
.single fertilization
.movement of cell or subcellular component
.microtubule motor activity .filopodium
.axoneme
.axonemal dynein complex
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 39 0
2014-09-19protein level
1 29 0
2014-05-27protein level
1 29 0
2014-02-25protein level
1 29 0
2013-12-09protein level
1 20 0
2013-11-01protein level
1 17 0
2013-09-12protein level
1 17 0
2013-08-17protein level
1 17 0
2013-07-15transcript level
1 13 0
2013-06-11transcript level
1 13 0
2013-02-12transcript level
1 11 0
2012-12-20transcript level
1 11 0
2012-10-30transcript level
1 9 0
2012-10-07transcript level
1 9 0
2012-08-24transcript level
1 9 0
2012-07-28transcript level
1 9 0
2012-06-08transcript level
1 12 0
2012-05-07transcript level
1 11 0
2012-04-10transcript level
1 11 0
2012-01-13transcript level
1 8 0
2011-12-20transcript level
1 8 0
2011-11-11transcript level
1 8 0
2011-08-23transcript level
1 8 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14645-1
9 6 0 29643.4506
NX_O14645-2
1 6 0 15573.0514
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-395638,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
2 EBI-395638,EBI-747107 SIAH1  
  .positive regulation of intrinsic apoptotic signaling pathway
.neuron apoptotic process
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 11 more...
.ubiquitin protein ligase activity
.identical protein binding
.ligase activity
  + 3 more...
.beta-catenin destruction complex
.plasma membrane
.cytosol
  + 3 more...
3 EBI-395638,EBI-912440 PRMT6  
  .negative regulation of transcription, DNA-templated
.histone H4-R3 methylation
.histone H3-R2 methylation
  + 6 more...
.histone methyltransferase activity (H2A-R3 specific)
.histone methyltransferase activity (H3-R2 specific)
.histone methyltransferase activity (H4-R3 specific)
  + 5 more...
.cytosol
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain33
embryonic tissue28
eye43
intestine12
kidney85
liver9
lung104
mammary gland33
muscle47
nerve64
ovary49
pancreas28
pharynx49
prostate73
skin9
testis43
thymus12
thyroid64
trachea57
uterus47
Health State
TissuesTPM*
normal41
breast (mammary gland) tumor53
germ cell tumor15
glioma46
head and neck tumor7
kidney tumor14
liver tumor10
lung tumor9
non-neoplasia62
ovarian tumor65
prostate cancer28
skin tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult35
embryoid body28
blastocyst16
neonate32
fetus43
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.6
adrenal gland10.2
appendix2.7
cerebral cortex8.7
colon4
duodenum3.4
esophagus3.7
gallbladder16.2
heart muscle4.1
kidney16.1
liver16.5
lung20.7
lymph node1.8
ovary20
pancreas11.4
placenta2.7
prostate15.5
salivary gland6
small intestine2.3
spleen2.2
stomach16.6
testis73.9
thyroid gland17.2
urinary bladder3.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602135, gene) Dynein, axonemal, light intermediate polypeptide 1; DNALI1OMIM


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