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> Protein (NX_O14662)
Protein (NX_O14662)
Protein
Gene SymbolSTX16 to neXtProt (NX_O14662)
DescriptionSyntaxin-16
Chromosome20
Location20q13.32 (57226328 ~ 57254582) to Ensembl
Sequene Features : Isoforms 6, Variants 50, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.Golgi ribbon formation
.vesicle docking
.retrograde transport, endosome to Golgi
  + 3 more...
.syntaxin binding
.SNAP receptor activity
.SNARE binding
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.Golgi cisterna
  + 11 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
6 50 0
2014-09-19protein level
6 33 0
2014-05-27protein level
6 33 0
2014-02-25protein level
6 33 0
2013-12-09protein level
6 25 0
2013-11-01protein level
6 25 0
2013-09-12protein level
6 25 1
2013-08-17protein level
6 25 1
2013-07-15protein level
6 18 1
2013-06-11protein level
6 18 1
2013-02-12protein level
6 11 2
2012-12-20protein level
5 12 2
2012-10-30protein level
5 13 2
2012-10-07protein level
5 13 1
2012-08-24protein level
5 13 1
2012-07-28protein level
5 13 1
2012-06-08protein level
5 18 1
2012-05-07protein level
4 13 1
2012-04-10protein level
4 13 1
2012-01-13protein level
4 10 1
2011-12-20protein level
4 10 1
2011-11-11protein level
4 10 1
2011-08-23protein level
4 10 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14662-1
1 16 0 37008.1361
NX_O14662-2
1 15 0 34791.0399
NX_O14662-3
1 5 0 13009.6456
NX_O14662-4
0 16 0 35277.2349
NX_O14662-5
1 16 0 36521.9411
NX_O14662-6
0 14 0 31054.0605
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2853548,EBI-10191195 VAMP5  
  .Golgi to plasma membrane protein transport
.cell differentiation
.skeletal muscle tissue development
  + 4 more...
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.integral component of organelle membrane
  + 9 more...
2 EBI-2853548,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
3 EBI-2853548,EBI-3921185 NAPB  
  .membrane fusion
.SNARE complex disassembly
.intracellular protein transport
.syntaxin binding
.soluble NSF attachment protein activity
.extracellular exosome
.SNARE complex
.vacuolar membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland212
ascites25
blood49
bone125
bone marrow20
brain57
cervix103
connective tissue46
ear62
embryonic tissue150
eye81
heart22
intestine47
kidney28
larynx42
liver43
lung65
lymph node133
mammary gland33
mouth105
muscle84
ovary118
pancreas70
parathyroid48
pituitary gland242
placenta105
prostate36
salivary gland148
skin66
spleen149
stomach62
testis18
thymus100
thyroid107
trachea19
uterus81
vascular38
Health State
TissuesTPM*
normal69
adrenal tumor237
breast (mammary gland) tumor53
cervical tumor144
chondrosarcoma132
colorectal tumor79
gastrointestinal tumor59
germ cell tumor68
glioma55
head and neck tumor104
kidney tumor58
leukemia105
liver tumor31
lung tumor48
lymphoma27
non-neoplasia41
ovarian tumor91
pancreatic tumor57
primitive neuroectodermal tumor of the CNS55
retinoblastoma107
skin tumor71
soft tissue/muscle tissue tumor47
uterine tumor133
Developmental Stage
TissuesTPM*
adult72
embryoid body171
blastocyst244
neonate32
fetus68
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue32
adrenal gland34.8
appendix54
bone marrow42.9
cerebral cortex29.6
colon25.9
duodenum33.5
esophagus25.2
gallbladder35.3
heart muscle21.4
kidney22.5
liver13.7
lung38.4
lymph node59.5
ovary40.4
pancreas12.8
placenta30.9
prostate36.3
salivary gland32.6
skin53.6
small intestine37
spleen55.6
stomach33.3
testis38.9
thyroid gland28.2
urinary bladder30.8
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Low
small intestineMedium
smooth muscleMedium
soft tissue 1Low
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#603233, phenotype) Pseudohypoparathyroidism, type ib; PHP1BOMIM
2(*603666, gene) Syntaxin 16; STX16OMIM


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