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> Protein (NX_O14732)
Protein (NX_O14732)
Protein
Gene SymbolIMPA2 to neXtProt (NX_O14732)
DescriptionInositol monophosphatase 2
Chromosome18
Location18p11.21 (11981024 ~ 12030876) to Ensembl
Sequene Features : Isoforms 2, Variants 38, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.inositol phosphate dephosphorylation
.phosphatidylinositol phosphorylation
.small molecule metabolic process
  + 4 more...
.inositol monophosphate 4-phosphatase activity
.inositol monophosphate 3-phosphatase activity
.metal ion binding
  + 2 more...
.cytosol
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 38 1
2014-09-19protein level
2 25 1
2014-05-27protein level
2 25 1
2014-02-25protein level
2 25 1
2013-12-09protein level
2 19 1
2013-11-01protein level
2 17 0
2013-09-12protein level
2 17 0
2013-08-17protein level
2 17 0
2013-07-15protein level
2 11 0
2013-06-11protein level
2 11 0
2013-02-12protein level
2 6 0
2012-12-20protein level
2 6 0
2012-10-30protein level
2 9 0
2012-10-07protein level
2 9 0
2012-08-24protein level
2 9 0
2012-07-28protein level
2 9 0
2012-06-08protein level
2 2 0
2012-05-07protein level
2 2 0
2012-04-10protein level
2 2 0
2012-01-13protein level
2 2 0
2011-12-20protein level
2 2 0
2011-11-11protein level
2 2 0
2011-08-23protein level
2 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14732-1
1 12 0 31300.9669
NX_O14732-2
1 12 0 28493.532
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-725233,EBI-752410 IMPA1  
  .inositol phosphate dephosphorylation
.phosphatidylinositol phosphorylation
.small molecule metabolic process
  + 5 more...
.inositol monophosphate phosphatase activity
.inositol monophosphate 4-phosphatase activity
.inositol monophosphate 3-phosphatase activity
  + 6 more...
.extracellular exosome
.cytosol
.cytoplasm
2 EBI-725233,EBI-717567 UBA3  
  .regulation of cell cycle
.protein neddylation
.innate immune response
  + 4 more...
.protein heterodimerization activity
.NEDD8 activating enzyme activity
.acid-amino acid ligase activity
.ATP binding
.cytosol
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood73
bone marrow41
brain11
cervix164
embryonic tissue79
eye81
heart22
intestine51
kidney61
larynx85
liver38
lung62
lymph22
mammary gland19
mouth15
muscle112
ovary68
pancreas32
pharynx24
placenta173
prostate42
salivary gland246
skin66
spleen37
stomach146
testis13
uterus60
Health State
TissuesTPM*
normal36
breast (mammary gland) tumor21
cervical tumor231
chondrosarcoma12
colorectal tumor79
gastrointestinal tumor75
germ cell tumor125
glioma46
head and neck tumor59
kidney tumor72
leukemia105
liver tumor83
lung tumor77
lymphoma13
non-neoplasia20
ovarian tumor52
pancreatic tumor66
primitive neuroectodermal tumor of the CNS15
prostate cancer77
retinoblastoma279
skin tumor55
soft tissue/muscle tissue tumor23
uterine tumor88
Developmental Stage
TissuesTPM*
adult58
embryoid body57
blastocyst113
fetus28
infant85
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13.8
adrenal gland9
appendix16.3
bone marrow23.3
cerebral cortex3.6
colon50.4
duodenum27.7
esophagus113
gallbladder29.7
heart muscle10.7
kidney169.3
liver12.9
lung33.3
lymph node8.2
ovary13
pancreas183.1
placenta47.6
prostate18.3
salivary gland17
skin140.4
small intestine34.9
spleen14.5
stomach57.2
testis9.6
thyroid gland24.5
urinary bladder20.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605922, gene) Myo-inositol monophosphatase 2; IMPA2OMIM


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