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> Protein (NX_O14737)
Protein (NX_O14737)
Protein
Gene SymbolPDCD5 to neXtProt (NX_O14737)
DescriptionProgrammed cell death protein 5
Chromosome19
Location19q13.11 (33071974 ~ 33078358) to Ensembl
Sequene Features : Isoforms 2, Variants 19, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of chaperone-mediated protein folding
.positive regulation of protein import into mitochondrial outer membrane
.positive regulation of release of cytochrome c from mitochondria
  + 5 more...
.beta-tubulin binding
.acetyltransferase activator activity
.heparin binding
.DNA binding
.extracellular exosome
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 19 8
2014-09-19protein level
1 15 8
2014-05-27protein level
1 15 8
2014-02-25protein level
1 15 8
2013-12-09protein level
1 11 8
2013-11-01protein level
1 11 6
2013-09-12protein level
1 11 6
2013-08-17protein level
1 11 6
2013-07-15protein level
1 6 3
2013-06-11protein level
1 6 3
2013-02-12protein level
1 4 3
2012-12-20protein level
1 4 3
2012-10-30protein level
1 5 3
2012-10-07protein level
1 5 3
2012-08-24protein level
1 5 3
2012-07-28protein level
1 5 3
2012-06-08protein level
1 6 3
2012-05-07protein level
1 3 3
2012-04-10protein level
1 3 3
2012-01-13protein level
1 2 3
2011-12-20protein level
1 2 3
2011-11-11protein level
1 2 3
2011-08-23protein level
1 2 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14737-1
2 5 0 14276.299
NX_O14737-2
2 5 0 14987.6416
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites25
blood16
bone27
brain16
connective tissue134
embryonic tissue18
eye33
heart11
intestine56
kidney28
liver38
lung17
lymph22
lymph node33
mammary gland46
mouth15
muscle37
nerve64
pancreas32
pharynx24
placenta35
prostate73
skin9
spleen18
stomach10
testis32
trachea19
uterus64
vascular19
Health State
TissuesTPM*
normal34
breast (mammary gland) tumor10
colorectal tumor26
gastrointestinal tumor16
germ cell tumor3
head and neck tumor14
kidney tumor43
leukemia10
liver tumor10
lung tumor9
lymphoma41
non-neoplasia10
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
prostate cancer67
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor191
uterine tumor33
Developmental Stage
TissuesTPM*
adult43
embryoid body14
blastocyst16
fetus34
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue39.9
adrenal gland53.7
appendix42
bone marrow18.4
cerebral cortex33.6
colon45.7
duodenum34
esophagus33.6
gallbladder19.1
heart muscle47.7
kidney38.9
liver27.7
lung30.6
lymph node32.9
ovary28.7
pancreas28.2
placenta34.8
prostate33.9
salivary gland25.4
skin28.1
small intestine33.6
spleen28.1
stomach36.8
testis69.9
thyroid gland22
urinary bladder29.1
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebral cortexLow
colonHigh
duodenumHigh
endometrium 1Low
endometrium 2Medium
esophagusLow
fallopian tubeHigh
gallbladderMedium
kidneyLow
lungMedium
lymph nodeLow
nasopharynxLow
oral mucosaMedium
ovaryMedium
pancreasLow
parathyroid glandMedium
placentaHigh
rectumHigh
salivary glandLow
seminal vesicleLow
skin 1Medium
skin 2Low
small intestineMedium
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Low
stomach 2Medium
testisHigh
thyroid glandLow
tonsilHigh
urinary bladderHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604583, gene) Programmed cell death 5; PDCD5OMIM


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