Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O14791)
Protein (NX_O14791)
Protein
Gene SymbolAPOL1 to neXtProt (NX_O14791)
DescriptionApolipoprotein L1
Chromosome22
Location22q12.3 (36649056 ~ 36663576) to Ensembl
Sequene Features : Isoforms 3, Variants 71, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.chloride transmembrane transport
.innate immune response
.lipoprotein metabolic process
  + 6 more...
.lipid binding
.chloride channel activity
.blood microparticle
.high-density lipoprotein particle
.very-low-density lipoprotein particle
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 71 2
2014-09-19protein level
3 56 2
2014-05-27protein level
3 56 2
2014-02-25protein level
3 56 2
2013-12-09protein level
3 45 2
2013-11-01protein level
3 44 2
2013-09-12protein level
3 44 2
2013-08-17protein level
3 44 2
2013-07-15protein level
3 34 1
2013-06-11protein level
3 34 1
2013-02-12protein level
3 25 9
2012-12-20protein level
2 25 6
2012-10-30protein level
2 29 6
2012-10-07protein level
2 29 3
2012-08-24protein level
2 26 3
2012-07-28protein level
2 25 3
2012-06-08protein level
2 28 3
2012-05-07protein level
2 28 3
2012-04-10protein level
2 28 3
2012-01-13protein level
2 15 3
2011-12-20protein level
2 15 3
2011-11-11protein level
2 15 3
2011-08-23protein level
2 15 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14791-1
0 17 0 43946.7673
NX_O14791-2
1 16 0 45889.7234
NX_O14791-3
1 15 0 42131.8265
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1221934,EBI-396137 CDC23  
  .protein K11-linked ubiquitination
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
.positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
  + 11 more...
.ubiquitin-protein transferase activity .cytosol
.anaphase-promoting complex
.nucleoplasm
.intracellular
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland60
ascites25
bladder234
blood49
bone69
brain68
cervix164
connective tissue261
eye14
heart22
intestine112
kidney180
larynx213
liver116
lung164
lymph node11
mammary gland257
mouth211
muscle28
ovary98
pancreas14
pharynx122
placenta67
prostate100
skin28
spleen1086
stomach721
testis9
thymus288
trachea231
uterus163
vascular58
Health State
TissuesTPM*
normal90
bladder carcinoma113
breast (mammary gland) tumor408
cervical tumor202
chondrosarcoma36
colorectal tumor44
gastrointestinal tumor582
germ cell tumor18
glioma55
head and neck tumor141
kidney tumor290
leukemia21
liver tumor145
lung tumor29
lymphoma13
non-neoplasia455
ovarian tumor78
pancreatic tumor28
prostate cancer19
skin tumor39
soft tissue/muscle tissue tumor7
uterine tumor177
Developmental Stage
TissuesTPM*
adult128
fetus3
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue40.9
adrenal gland13.6
appendix61.3
bone marrow3.1
cerebral cortex5.3
colon27.7
duodenum29.4
esophagus18.4
gallbladder79.8
heart muscle15.2
kidney21.3
liver119
lung58.1
lymph node24.7
ovary27.2
pancreas4.5
placenta47.7
prostate24
salivary gland23.5
skin6.5
small intestine26.9
spleen54.3
stomach68.9
testis11.5
thyroid gland9.2
urinary bladder107.6
Tissues
TissuesExpression level
colonLow
duodenumLow
kidneyLow
pancreasLow
rectumLow
skeletal muscleLow
small intestineLow
stomach 2Low
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603743, gene) Apolipoprotein l-i; APOL1OMIM
2(#612551, phenotype) Focal segmental glomerulosclerosis 4, susceptibility to; FSGS4OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center