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> Protein (NX_O14924)
Protein (NX_O14924)
Protein
Gene SymbolRGS12 to neXtProt (NX_O14924)
DescriptionRegulator of G-protein signaling 12
Chromosome4
Location4p16.3 (3294755 ~ 3441640) to Ensembl
Sequene Features : Isoforms 7, Variants 184, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of catalytic activity
.positive regulation of GTPase activity
.termination of G-protein coupled receptor signaling pathway
  + 2 more...
.GTPase regulator activity
.GTPase activator activity
.receptor signaling protein activity
.nuclear matrix
.plasma membrane
.cytoplasm
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
7 184 6
2014-09-19protein level
7 145 6
2014-05-27protein level
7 145 6
2014-02-25protein level
6 145 4
2013-12-09protein level
6 101 4
2013-11-01protein level
6 98 4
2013-09-12protein level
6 98 4
2013-08-17protein level
4 97 4
2013-07-15protein level
4 71 4
2013-06-11protein level
4 71 4
2013-02-12protein level
4 39 24
2012-12-20protein level
4 40 24
2012-10-30protein level
4 47 24
2012-10-07protein level
4 47 6
2012-08-24protein level
4 45 6
2012-07-28protein level
4 45 6
2012-06-08protein level
4 3 6
2012-05-07protein level
4 3 6
2012-04-10protein level
4 3 6
2012-01-13protein level
4 3 6
2011-12-20protein level
4 7 6
2011-11-11protein level
4 7 6
2011-08-23protein level
4 7 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14924-1
0 64 0 156260.0816
NX_O14924-2
0 34 0 84842.0224
NX_O14924-3
1 33 0 85913.4733
NX_O14924-4
1 59 0 149499.6556
NX_O14924-5
0 55 0 126292.9706
NX_O14924-6
1 26 0 61069.2867
NX_O14924-7
0 25 0 54874.9114
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone41
bone marrow20
brain66
cervix41
connective tissue20
embryonic tissue37
esophagus49
eye100
heart44
intestine64
kidney85
liver9
lung107
lymph node44
mammary gland52
mouth15
muscle28
nerve64
ovary59
pancreas42
parathyroid48
placenta14
prostate26
skin80
spleen37
stomach20
testis20
thymus50
thyroid21
trachea19
uterus47
Health State
TissuesTPM*
normal47
breast (mammary gland) tumor53
chondrosarcoma48
colorectal tumor26
esophageal tumor57
gastrointestinal tumor16
germ cell tumor26
glioma158
kidney tumor29
leukemia21
liver tumor10
lung tumor9
non-neoplasia62
ovarian tumor78
pancreatic tumor57
prostate cancer28
skin tumor119
soft tissue/muscle tissue tumor23
uterine tumor77
Developmental Stage
TissuesTPM*
adult39
embryoid body28
blastocyst48
fetus77
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.8
adrenal gland9.2
appendix11.7
bone marrow4.1
cerebral cortex33.9
colon8.4
duodenum11.2
esophagus26.4
gallbladder12.4
heart muscle8.8
kidney19.4
liver8.5
lung21.1
lymph node9
ovary15.6
pancreas4.7
placenta9.9
prostate19.1
salivary gland8.3
skin31.8
small intestine15.3
spleen12.5
stomach8.9
testis12.1
thyroid gland10.2
urinary bladder13.5
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*602512, gene) Regulator of g protein signaling 12; RGS12OMIM


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