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> Protein (NX_O14925)
Protein (NX_O14925)
Protein
Gene SymbolTIMM23 to neXtProt (NX_O14925)
DescriptionMitochondrial import inner membrane translocase subunit Tim23
Chromosome10
Location10q11.23 (51592080 ~ 51623365) to Ensembl
Sequene Features : Isoforms 1, Variants 10, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.protein targeting to mitochondrion
.P-P-bond-hydrolysis-driven protein transmembrane transporter activity .integral component of mitochondrial inner membrane
.mitochondrial intermembrane space
.mitochondrial inner membrane presequence translocase complex
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 10 0
2014-09-19protein level
1 8 0
2014-05-27protein level
1 8 0
2014-02-25protein level
1 8 0
2013-12-09protein level
1 5 0
2013-11-01protein level
1 5 0
2013-09-12protein level
1 5 0
2013-08-17protein level
1 5 0
2013-07-15protein level
1 4 0
2013-06-11protein level
1 4 0
2013-02-12protein level
1 3 0
2012-12-20protein level
1 3 0
2012-10-30protein level
1 3 0
2012-10-07protein level
1 3 0
2012-08-24protein level
1 3 0
2012-07-28protein level
1 3 0
2012-06-08protein level
1 5 0
2012-05-07protein level
1 5 0
2012-04-10protein level
1 5 0
2012-01-13protein level
1 6 0
2011-12-20protein level
1 6 0
2011-11-11protein level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14925-1
10 0 0 21928.9293
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1047996,EBI-6570759 TIMM21  
  .cellular protein metabolic process
.mitochondrial respiratory chain complex IV assembly
.mitochondrial respiratory chain complex I assembly
  + 2 more...
.N/A .integral component of membrane
.mitochondrial inner membrane presequence translocase complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
bladder33
blood24
bone55
brain10
cervix82
connective tissue67
ear62
embryonic tissue4
eye33
heart11
intestine4
liver4
mammary gland6
placenta3
Health State
TissuesTPM*
normal26
adrenal tumor158
breast (mammary gland) tumor96
cervical tumor57
chondrosarcoma72
colorectal tumor44
gastrointestinal tumor16
germ cell tumor22
glioma37
head and neck tumor29
kidney tumor29
leukemia10
lung tumor29
lymphoma55
ovarian tumor13
pancreatic tumor28
primitive neuroectodermal tumor of the CNS47
prostate cancer67
retinoblastoma21
soft tissue/muscle tissue tumor63
uterine tumor44
Developmental Stage
TissuesTPM*
adult40
embryoid body14
neonate32
fetus53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue33
adrenal gland38
appendix31.2
bone marrow43.5
cerebral cortex30.8
colon38
duodenum45.6
esophagus38.8
gallbladder33.1
heart muscle62.1
kidney40.5
liver32.8
lung24.8
lymph node34.8
ovary17.4
pancreas13.2
placenta30.2
prostate31.9
salivary gland22.1
skin25.6
small intestine29.7
spleen20.3
stomach25.7
testis70.7
thyroid gland42.7
urinary bladder38.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605034, gene) Translocase of inner mitochondrial membrane 23, yeast, homolog of;OMIM


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