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> Protein (NX_O14944)
Protein (NX_O14944)
Protein
Gene SymbolEREG to neXtProt (NX_O14944)
DescriptionProepiregulin
Chromosome4
Location4q13.3 (75230860 ~ 75254468) to Ensembl
Sequene Features : Isoforms 1, Variants 31, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of smooth muscle cell differentiation
.negative regulation of epithelial cell proliferation
.positive regulation of smooth muscle cell proliferation
  + 36 more...
.growth factor activity
.epidermal growth factor receptor binding
.integral component of plasma membrane
.extracellular space
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 31 4
2014-09-19protein level
1 24 4
2014-05-27protein level
1 24 4
2014-02-25protein level
1 23 4
2013-12-09protein level
1 19 4
2013-11-01protein level
1 16 4
2013-09-12protein level
1 16 4
2013-08-17protein level
1 16 4
2013-07-15protein level
1 15 4
2013-06-11protein level
1 15 4
2013-02-12protein level
1 8 4
2012-12-20protein level
1 8 4
2012-10-30protein level
1 9 4
2012-10-07protein level
1 9 4
2012-08-24protein level
1 9 4
2012-07-28protein level
1 9 4
2012-06-08protein level
1 9 4
2012-05-07protein level
1 8 4
2012-04-10protein level
1 8 4
2012-01-13protein level
1 4 4
2011-12-20protein level
1 4 4
2011-11-11protein level
1 4 4
2011-08-23protein level
1 4 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14944-1
8 0 0 19031.3873
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood16
brain4
intestine17
kidney4
liver19
lung14
lymph node11
mouth15
muscle18
skin37
testis2
uterus4
Health State
TissuesTPM*
normal5
colorectal tumor35
gastrointestinal tumor16
glioma46
head and neck tumor7
liver tumor41
lung tumor29
uterine tumor11
Developmental Stage
TissuesTPM*
adult9
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.2
appendix13.5
bone marrow82.8
colon2.6
esophagus14.5
gallbladder6.6
skin6.2
small intestine2
urinary bladder4.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602061, gene) Epiregulin; EREGOMIM


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