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> Protein (NX_O14948)
Protein (NX_O14948)
Protein
Gene SymbolTFEC to neXtProt (NX_O14948)
DescriptionTranscription factor EC
Chromosome7
Location7q31.2 (115575202 ~ 115799950) to Ensembl
Sequene Features : Isoforms 4, Variants 69, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of nucleic acid-templated transcription
.positive regulation of transcription from RNA polymerase II promoter
.cellular response to heat
.transcription corepressor activity
.transcription coactivator activity
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 69 0
2014-09-19protein level
4 41 0
2014-05-27protein level
4 41 0
2014-02-25protein level
4 40 0
2013-12-09protein level
4 34 0
2013-11-01protein level
4 32 0
2013-09-12protein level
4 32 0
2013-08-17protein level
4 32 0
2013-07-15protein level
4 22 0
2013-06-11protein level
4 22 0
2013-02-12protein level
4 9 0
2012-12-20protein level
4 8 0
2012-10-30protein level
4 9 0
2012-10-07protein level
4 9 0
2012-08-24protein level
4 6 0
2012-07-28protein level
4 6 0
2012-06-08protein level
4 6 0
2012-05-07protein level
4 6 0
2012-04-10protein level
4 6 0
2012-01-13protein level
4 6 0
2011-12-20protein level
4 6 0
2011-11-11protein level
4 6 0
2011-08-23protein level
4 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14948-1
3 8 2 38763.4718
NX_O14948-2
0 9 2 35511.9769
NX_O14948-3
0 4 2 22638.8638
NX_O14948-4
1 6 2 31538.1907
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3916574,EBI-3921185 NAPB  
  .membrane fusion
.SNARE complex disassembly
.intracellular protein transport
.syntaxin binding
.soluble NSF attachment protein activity
.extracellular exosome
.SNARE complex
.vacuolar membrane
2 EBI-3916574,EBI-10305240 DEFB127  
  .innate immune response
.defense response to bacterium
.N/A .cell surface
.extracellular region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood65
bone marrow61
brain5
connective tissue20
kidney75
lung11
lymph45
mammary gland6
muscle18
ovary9
pancreas4
parathyroid48
placenta10
stomach20
testis2
thyroid42
trachea19
uterus8
Health State
TissuesTPM*
normal10
breast (mammary gland) tumor10
germ cell tumor7
head and neck tumor14
kidney tumor14
leukemia63
lymphoma27
non-neoplasia10
soft tissue/muscle tissue tumor23
uterine tumor22
Developmental Stage
TissuesTPM*
adult13
neonate64
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.8
adrenal gland3.1
appendix21.4
bone marrow10.3
cerebral cortex1.6
colon2.8
duodenum4.6
esophagus1.1
gallbladder5.5
kidney32.6
liver1.5
lung7.4
lymph node24.6
ovary1.2
placenta3.9
small intestine10.8
spleen12.1
stomach3.6
testis2.1
thyroid gland1.1
urinary bladder5.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604732, gene) Transcription factor ec; TFECOMIM


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