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> Protein (NX_O14950)
Protein (NX_O14950)
Protein
Gene SymbolMYL12B to neXtProt (NX_O14950)
DescriptionMyosin regulatory light chain 12B
Chromosome18
Location18p11.31 (3261907 ~ 3278282) to Ensembl
Sequene Features : Isoforms 1, Variants 17, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ephrin receptor signaling pathway
.regulation of cell shape
.axon guidance
  + 2 more...
.calcium ion binding .extracellular exosome
.apical part of cell
.Z disc
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 17 2
2014-09-19protein level
1 9 2
2014-05-27protein level
1 9 5
2014-02-25protein level
1 9 5
2013-12-09protein level
1 9 5
2013-11-01protein level
1 9 4
2013-09-12protein level
1 9 4
2013-08-17protein level
1 9 4
2013-07-15protein level
1 4 4
2013-06-11protein level
1 4 4
2013-02-12protein level
1 1 5
2012-12-20protein level
1 1 5
2012-10-30protein level
1 1 5
2012-10-07protein level
1 1 5
2012-08-24protein level
1 1 5
2012-07-28protein level
1 1 5
2012-06-08protein level
1 7 5
2012-05-07protein level
1 11 5
2012-04-10protein level
1 11 5
2012-01-13protein level
1 10 5
2011-12-20protein level
1 10 5
2011-11-11protein level
1 10 5
2011-08-23protein level
1 10 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14950-1
1 0 8 19766.4614
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1642165,EBI-1052928 MYH11  
  .activation of mitophagy in response to mitochondrial depolarization
.cardiac muscle fiber development
.elastic fiber assembly
  + 6 more...
.structural constituent of muscle
.ATP binding
.motor activity
.extracellular exosome
.melanosome
.myosin filament
  + 4 more...
2 EBI-1642165,EBI-353944 ACTB  
  .platelet aggregation
.membrane organization
.'de novo' posttranslational protein folding
  + 17 more...
.nitric-oxide synthase binding
.identical protein binding
.Tat protein binding
  + 3 more...
.blood microparticle
.MLL5-L complex
.extracellular exosome
  + 16 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland273
ascites301
bladder669
blood441
bone684
bone marrow451
brain52
cervix82
connective tissue228
ear372
embryonic tissue310
esophagus49
eye143
heart178
intestine103
kidney61
liver77
lung146
lymph node89
mammary gland218
mouth15
nerve128
ovary98
pancreas187
parathyroid339
pharynx466
pituitary gland60
placenta120
prostate84
salivary gland98
skin128
spleen37
stomach344
testis87
thyroid364
umbilical cord508
uterus323
vascular251
Health State
TissuesTPM*
normal117
adrenal tumor553
bladder carcinoma1194
breast (mammary gland) tumor805
cervical tumor115
chondrosarcoma627
colorectal tumor151
esophageal tumor57
gastrointestinal tumor168
germ cell tumor49
glioma9
head and neck tumor171
kidney tumor130
leukemia95
liver tumor52
lung tumor58
lymphoma27
non-neoplasia51
ovarian tumor105
pancreatic tumor180
primitive neuroectodermal tumor of the CNS15
prostate cancer67
retinoblastoma21
skin tumor47
soft tissue/muscle tissue tumor71
uterine tumor654
Developmental Stage
TissuesTPM*
adult533
embryoid body514
blastocyst195
neonate289
fetus152
infant42
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue185.5
adrenal gland316.6
appendix213.4
bone marrow168.3
cerebral cortex102.2
colon367.6
duodenum335.4
esophagus333.9
gallbladder268.4
heart muscle209.8
kidney295.9
liver194.6
lung328.2
lymph node233.9
ovary182.2
pancreas80.8
placenta337.2
prostate198.9
salivary gland149.7
skin195.7
small intestine321.6
spleen191.8
stomach256.2
testis147
thyroid gland299.1
urinary bladder337.7
Tissues
TissuesExpression level
breastMedium
cerebral cortexLow
colonMedium
heart muscleMedium
kidneyLow
skeletal muscleMedium
smooth muscleMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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