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> Protein (NX_O14978)
Protein (NX_O14978)
Protein
Gene SymbolZNF263 to neXtProt (NX_O14978)
DescriptionZinc finger protein 263
Chromosome16
Location16p13.3 (3313743 ~ 3351401) to Ensembl
Sequene Features : Isoforms 1, Variants 84, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of transcription, DNA-templated
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.microtubule cytoskeleton
.cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 84 0
2014-09-19protein level
1 67 0
2014-05-27protein level
1 67 0
2014-02-25protein level
1 67 0
2013-12-09protein level
1 47 0
2013-11-01protein level
1 43 0
2013-09-12protein level
1 43 0
2013-08-17protein level
1 43 0
2013-07-15transcript level
1 31 0
2013-06-11transcript level
1 31 0
2013-02-12transcript level
1 18 0
2012-12-20transcript level
1 15 0
2012-10-30transcript level
1 21 0
2012-10-07transcript level
1 21 0
2012-08-24transcript level
1 21 0
2012-07-28transcript level
1 21 0
2012-06-08transcript level
1 22 0
2012-05-07transcript level
1 18 0
2012-04-10transcript level
1 18 0
2012-01-13transcript level
1 8 0
2011-12-20transcript level
1 8 0
2011-11-11transcript level
1 8 0
2011-08-23transcript level
1 8 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O14978-1
32 0 4 77249.5144
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744493,EBI-750020 CLK2  
  .protein autophosphorylation
.negative regulation of gluconeogenesis
.regulation of RNA splicing
  + 3 more...
.ATP binding
.protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity
.nuclear speck
.nucleoplasm
.nucleus
2 EBI-744493,EBI-745579 CLK3  
  .protein autophosphorylation
.regulation of RNA splicing
.protein phosphorylation
.poly(A) RNA binding
.ATP binding
.protein tyrosine kinase activity
  + 2 more...
.intermediate filament cytoskeleton
.nuclear speck
.membrane
  + 3 more...
3 EBI-744493,EBI-5666657 GPATCH2L  
  .N/A .N/A .N/A
4 EBI-744493,EBI-750484 FAM115A  
  .positive regulation of anion channel activity
.positive regulation of protein targeting to membrane
.negative regulation of cell migration
.transport
.ion channel binding .plasma membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
blood57
bone13
bone marrow61
brain40
cervix164
connective tissue67
embryonic tissue75
eye57
heart11
intestine25
kidney28
lung23
lymph67
lymph node22
mammary gland59
mouth75
muscle18
nerve64
ovary78
pancreas14
placenta21
prostate31
skin9
spleen18
stomach20
testis45
thymus75
thyroid107
tonsil58
trachea19
uterus43
vascular19
Health State
TissuesTPM*
normal32
adrenal tumor79
breast (mammary gland) tumor75
cervical tumor144
chondrosarcoma72
colorectal tumor35
gastrointestinal tumor16
germ cell tumor106
glioma37
head and neck tumor37
kidney tumor72
leukemia52
lung tumor48
lymphoma55
non-neoplasia51
ovarian tumor65
pancreatic tumor9
primitive neuroectodermal tumor of the CNS78
prostate cancer28
retinoblastoma43
soft tissue/muscle tissue tumor23
uterine tumor66
Developmental Stage
TissuesTPM*
adult35
embryoid body71
blastocyst113
fetus44
infant85
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17
adrenal gland15.8
appendix17.2
bone marrow12.4
cerebral cortex17.2
colon15.8
duodenum13.9
esophagus14.8
gallbladder18.5
heart muscle9.6
kidney14
liver8.7
lung19.6
lymph node22.5
ovary28.1
pancreas10.4
placenta19.1
prostate20
salivary gland14.6
skin18.4
small intestine13.2
spleen21.4
stomach16.4
testis19
thyroid gland21.6
urinary bladder18.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604191, gene) Zinc finger protein 263; ZNF263OMIM


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