Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O15015)
Protein (NX_O15015)
Protein
Gene SymbolZNF646 to neXtProt (NX_O15015)
DescriptionZinc finger protein 646
Chromosome16
Location16p11.2 (31085743 ~ 31095517) to Ensembl
Sequene Features : Isoforms 2, Variants 238, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 238 1
2014-09-19protein level
2 185 1
2014-05-27protein level
2 185 2
2014-02-25protein level
2 185 2
2013-12-09protein level
2 129 2
2013-11-01protein level
2 125 2
2013-09-12protein level
2 125 2
2013-08-17protein level
2 125 2
2013-07-15protein level
2 94 2
2013-06-11protein level
2 94 2
2013-02-12protein level
2 55 0
2012-12-20protein level
2 57 0
2012-10-30protein level
2 60 0
2012-10-07protein level
2 60 0
2012-08-24protein level
2 55 0
2012-07-28protein level
2 55 0
2012-06-08protein level
2 56 0
2012-05-07protein level
2 51 0
2012-04-10protein level
2 51 0
2012-01-13protein level
2 24 0
2011-12-20protein level
2 24 0
2011-11-11protein level
2 24 0
2011-08-23protein level
2 24 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15015-1
2 81 0 200635.1666
NX_O15015-2
2 81 0 200698.3106
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-745608,EBI-3952014 PRKG1  
  .activation of mitophagy in response to mitochondrial depolarization
.negative regulation of platelet aggregation
.relaxation of vascular smooth muscle
  + 9 more...
.cGMP binding
.ATP binding
.calcium channel regulator activity
.cGMP-dependent protein kinase activity
.plasma membrane
.cytosol
.Golgi apparatus
.cytoplasm
2 EBI-745608,EBI-6598631 EMSY  
  .chromatin modification
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA repair
.N/A .nucleoplasm
3 EBI-745608,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
blood8
bone marrow20
brain7
embryonic tissue9
eye28
heart11
intestine34
kidney14
lung8
lymph90
lymph node11
mammary gland33
mouth15
muscle9
pancreas9
placenta3
prostate26
skin4
testis32
tonsil117
uterus25
Health State
TissuesTPM*
normal8
breast (mammary gland) tumor53
colorectal tumor44
gastrointestinal tumor16
germ cell tumor3
glioma27
head and neck tumor7
kidney tumor14
leukemia10
lung tumor19
lymphoma55
pancreatic tumor9
primitive neuroectodermal tumor of the CNS15
prostate cancer38
retinoblastoma64
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor22
Developmental Stage
TissuesTPM*
adult13
blastocyst32
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.5
adrenal gland2.6
appendix5.5
bone marrow5
cerebral cortex3.2
colon3.9
duodenum4.8
esophagus3.2
gallbladder3.9
heart muscle2.3
kidney3.5
lung4.1
lymph node5.6
ovary5.3
pancreas2.2
placenta3.5
prostate3.8
salivary gland4.4
skin4.2
small intestine4.2
spleen7.7
stomach5.1
testis22.4
thyroid gland3.7
urinary bladder3.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center