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> Protein (NX_O15072)
Protein (NX_O15072)
Protein
Gene SymbolADAMTS3 to neXtProt (NX_O15072)
DescriptionA disintegrin and metalloproteinase with thrombospondin motifs 3
Chromosome4
Location4q13.3 (73146686 ~ 73434516) to Ensembl
Sequene Features : Isoforms 1, Variants 186, PTMs 28 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of vascular endothelial growth factor signaling pathway
.extracellular fibril organization
.collagen biosynthetic process
  + 5 more...
.zinc ion binding
.heparin binding
.metalloendopeptidase activity
.endopeptidase activity
.extracellular exosome
.extracellular space
.proteinaceous extracellular matrix
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 186 28
2014-09-19protein level
1 147 28
2014-05-27protein level
1 147 28
2014-02-25protein level
1 145 28
2013-12-09protein level
1 121 28
2013-11-01protein level
1 119 28
2013-09-12protein level
1 119 23
2013-08-17protein level
1 119 23
2013-07-15transcript level
1 80 15
2013-06-11transcript level
1 80 15
2013-02-12transcript level
1 34 15
2012-12-20transcript level
1 34 15
2012-10-30transcript level
1 41 15
2012-10-07transcript level
1 41 15
2012-08-24transcript level
1 25 15
2012-07-28transcript level
1 25 15
2012-06-08transcript level
1 26 15
2012-05-07transcript level
1 26 15
2012-04-10transcript level
1 26 15
2012-01-13transcript level
1 14 15
2011-12-20transcript level
1 14 15
2011-11-11transcript level
1 14 15
2011-08-23transcript level
1 14 15
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15072-1
50 0 4 135514.9995
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
blood8
brain7
embryonic tissue9
liver9
lung2
mammary gland19
muscle9
placenta17
testis9
Health State
TissuesTPM*
normal6
adrenal tumor79
breast (mammary gland) tumor32
germ cell tumor7
non-neoplasia10
Developmental Stage
TissuesTPM*
adult6
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.9
appendix1.2
ovary2.2
placenta1.5
testis2.5
thyroid gland1.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605011, gene) A disintegrin-like and metalloproteinase with thrombospondin typeOMIM


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