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> Protein (NX_O15173)
Protein (NX_O15173)
Protein
Gene SymbolPGRMC2 to neXtProt (NX_O15173)
DescriptionMembrane-associated progesterone receptor component 2
Chromosome4
Location4q28.2 (129190397 ~ 129209984) to Ensembl
Sequene Features : Isoforms 2, Variants 10, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.steroid hormone mediated signaling pathway .heme binding
.steroid binding
.steroid hormone receptor activity
.integral component of membrane
.membrane
.endomembrane system
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 10 8
2014-09-19protein level
2 9 8
2014-05-27protein level
2 9 8
2014-02-25protein level
2 9 8
2013-12-09protein level
2 9 8
2013-11-01protein level
1 8 6
2013-09-12protein level
1 8 6
2013-08-17protein level
1 8 6
2013-07-15protein level
1 2 5
2013-06-11protein level
1 2 5
2013-02-12protein level
1 1 5
2012-12-20protein level
1 1 5
2012-10-30protein level
1 0 5
2012-10-07protein level
1 0 5
2012-08-24protein level
1 0 5
2012-07-28protein level
1 0 5
2012-06-08protein level
1 0 5
2012-05-07protein level
1 7 5
2012-04-10protein level
1 7 5
2012-01-13protein level
1 5 5
2011-12-20protein level
1 5 5
2011-11-11protein level
1 5 5
2011-08-23protein level
1 5 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15173-1
1 7 1 23803.6631
NX_O15173-2
1 7 1 26153.8718
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
bladder66
blood65
bone125
bone marrow61
brain57
cervix144
connective tissue87
ear124
embryonic tissue84
eye90
heart111
intestine38
kidney147
larynx42
liver112
lung50
lymph node77
mammary gland72
mouth30
muscle47
ovary59
pancreas93
parathyroid437
pituitary gland242
placenta190
prostate52
skin147
spleen18
stomach135
testis71
thymus37
thyroid107
trachea38
umbilical cord290
uterus38
vascular58
Health State
TissuesTPM*
normal93
adrenal tumor79
breast (mammary gland) tumor42
cervical tumor86
chondrosarcoma144
colorectal tumor35
gastrointestinal tumor84
germ cell tumor34
glioma65
head and neck tumor44
kidney tumor101
leukemia63
liver tumor104
lung tumor19
lymphoma55
non-neoplasia144
ovarian tumor78
pancreatic tumor104
primitive neuroectodermal tumor of the CNS94
prostate cancer48
retinoblastoma21
skin tumor47
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult91
embryoid body128
blastocyst97
neonate128
fetus114
infant85
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue86.1
adrenal gland52.3
appendix39.1
bone marrow26
cerebral cortex33.2
colon67.4
duodenum106.3
esophagus54.7
gallbladder57.7
heart muscle41.5
kidney78.3
liver88.1
lung40.4
lymph node30.2
ovary51.5
pancreas35
placenta93.6
prostate51.1
salivary gland41.9
skin80.8
small intestine110.2
spleen27.4
stomach77.6
testis39.5
thyroid gland62.2
urinary bladder60
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607735, gene) Progesterone receptor membrane component 2; PGRMC2OMIM


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