Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O15209)
Protein (NX_O15209)
Protein
Gene SymbolZBTB22 to neXtProt (NX_O15209)
DescriptionZinc finger and BTB domain-containing protein 22
Chromosome6
Location6p21.32 (33282183 ~ 33285719) to Ensembl
Sequene Features : Isoforms 1, Variants 71, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 71 0
2014-09-19protein level
1 51 0
2014-05-27protein level
1 51 0
2014-02-25protein level
1 25 0
2013-12-09protein level
1 9 0
2013-11-01protein level
1 9 0
2013-09-12protein level
1 9 0
2013-08-17protein level
1 9 0
2013-07-15transcript level
1 9 0
2013-06-11transcript level
1 9 0
2013-02-12transcript level
1 9 0
2012-12-20transcript level
1 9 0
2012-10-30transcript level
1 13 0
2012-10-07transcript level
1 13 0
2012-08-24transcript level
1 13 0
2012-07-28transcript level
1 13 0
2012-06-08transcript level
1 18 0
2012-05-07transcript level
1 18 0
2012-04-10transcript level
1 14 0
2012-01-13transcript level
1 13 0
2011-12-20transcript level
1 13 0
2011-11-11transcript level
1 11 0
2011-08-23transcript level
1 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15209-1
22 0 1 65560.9065
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-723574,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
2 EBI-723574,EBI-714158 PIN1  
  .negative regulation of cell motility
.negative regulation of ERK1 and ERK2 cascade
.regulation of pathway-restricted SMAD protein phosphorylation
  + 11 more...
.phosphothreonine binding
.phosphoserine binding
.GTPase activating protein binding
  + 2 more...
.midbody
.nuclear speck
.cytoplasm
  + 2 more...
3 EBI-723574,EBI-6654703 RBM39  
  .RNA splicing
.mRNA processing
.RNA processing
  + 2 more...
.poly(A) RNA binding
.nucleotide binding
.nuclear speck
.microtubule cytoskeleton
.microtubule organizing center
.nucleoplasm
4 EBI-723574,EBI-348259 MCRS1  
  .histone H4-K16 acetylation
.histone H4-K8 acetylation
.histone H4-K5 acetylation
  + 6 more...
.N/A .MLL1 complex
.Ino80 complex
.cell junction
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
bone13
bone marrow20
brain21
cervix20
connective tissue13
embryonic tissue32
eye33
heart22
intestine25
kidney14
liver4
lung38
lymph22
mammary gland6
ovary19
pancreas23
pharynx49
placenta10
prostate5
skin28
spleen18
testis2
uterus30
Health State
TissuesTPM*
normal20
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma48
colorectal tumor44
germ cell tumor3
glioma65
leukemia21
liver tumor10
lung tumor9
lymphoma13
non-neoplasia31
ovarian tumor26
pancreatic tumor9
primitive neuroectodermal tumor of the CNS15
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor31
uterine tumor33
Developmental Stage
TissuesTPM*
adult21
embryoid body28
blastocyst16
fetus41
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9
adrenal gland8.9
appendix6.6
bone marrow2.3
cerebral cortex9.6
colon8.5
duodenum6.4
esophagus8
gallbladder8.4
heart muscle7.7
kidney9.2
liver3.4
lung11.9
lymph node8
ovary13.8
pancreas4.3
placenta6.9
prostate10.2
salivary gland7.1
skin9.5
small intestine8.2
spleen10.9
stomach9.4
testis5
thyroid gland12.3
urinary bladder9.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611439, gene) Zinc finger- and btb domain-containing protein 22; ZBTB22OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center