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> Protein (NX_O15287)
Protein (NX_O15287)
Protein
Gene SymbolFANCG to neXtProt (NX_O15287)
DescriptionFanconi anemia group G protein
Chromosome9
Location9p13.3 (35073832 ~ 35080013) to Ensembl
Sequene Features : Isoforms 1, Variants 84, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.response to radiation
.spermatid development
.mitochondrion organization
  + 3 more...
.damaged DNA binding .Fanconi anaemia nuclear complex
.plasma membrane
.mitochondrion
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 84 5
2014-09-19protein level
1 69 5
2014-05-27protein level
1 69 5
2014-02-25protein level
1 68 5
2013-12-09protein level
1 55 5
2013-11-01protein level
1 55 5
2013-09-12protein level
1 55 5
2013-08-17protein level
1 55 5
2013-07-15protein level
1 42 1
2013-06-11protein level
1 42 1
2013-02-12protein level
1 22 1
2012-12-20protein level
1 24 1
2012-10-30protein level
1 26 1
2012-10-07protein level
1 26 1
2012-08-24protein level
1 21 1
2012-07-28protein level
1 21 1
2012-06-08protein level
1 26 1
2012-05-07protein level
1 24 1
2012-04-10protein level
1 24 1
2012-01-13protein level
1 19 1
2011-12-20protein level
1 19 1
2011-11-11protein level
1 19 1
2011-08-23protein level
1 16 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15287-1
31 0 0 68510.4321
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-81610,EBI-81570 FANCA  
  .regulation of cell proliferation
.female gonad development
.male gonad development
  + 3 more...
.N/A .Fanconi anaemia nuclear complex
.cytoplasm
.nucleolus
  + 2 more...
2 EBI-81610,EBI-351450 SPTAN1  
  .actin filament capping
.programmed cell death
.axon guidance
  + 2 more...
.calcium ion binding
.structural constituent of cytoskeleton
.actin binding
.extracellular exosome
.intracellular membrane-bounded organelle
.cuticular plate
  + 8 more...
3 EBI-81610,EBI-81589 FANCF  
  .activation of mitophagy in response to mitochondrial depolarization
.spermatogenesis
.DNA repair
.ovarian follicle development
.ubiquitin-protein transferase activity .Fanconi anaemia nuclear complex
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites75
bladder33
blood65
bone13
bone marrow82
brain41
cervix206
connective tissue40
embryonic tissue37
esophagus49
eye67
heart22
intestine17
kidney42
liver24
lung26
lymph203
lymph node44
mammary gland13
muscle18
ovary88
pancreas51
placenta21
prostate26
skin37
spleen56
stomach10
testis32
thymus112
thyroid64
trachea38
uterus77
Health State
TissuesTPM*
normal33
cervical tumor57
chondrosarcoma24
colorectal tumor8
esophageal tumor57
gastrointestinal tumor33
germ cell tumor68
glioma121
head and neck tumor22
kidney tumor58
leukemia74
liver tumor52
lung tumor38
lymphoma193
non-neoplasia31
ovarian tumor91
pancreatic tumor76
primitive neuroectodermal tumor of the CNS102
prostate cancer28
retinoblastoma193
skin tumor31
soft tissue/muscle tissue tumor95
uterine tumor44
Developmental Stage
TissuesTPM*
adult36
embryoid body14
blastocyst81
neonate64
fetus44
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.6
adrenal gland4.9
appendix9.7
bone marrow15.7
cerebral cortex5.1
colon8.7
duodenum6.5
esophagus7.9
gallbladder5.9
heart muscle2.7
kidney3.8
liver2
lung6
lymph node14
ovary12.1
pancreas4.3
placenta8
prostate7
salivary gland5
skin14
small intestine9.8
spleen9.3
stomach8.7
testis11.3
thyroid gland5.6
urinary bladder7.8
Tissues
TissuesExpression level
adrenal glandLow
appendixLow
bone marrowHigh
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexMedium
colonMedium
duodenumMedium
endometrium 1High
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyLow
lateral ventricleMedium
lungHigh
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skin 1Medium
skin 2High
small intestineMedium
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Low
testisLow
thyroid glandMedium
tonsilLow
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602956, gene) Fancg gene; FANCGOMIM
2(#614082, phenotype) Fanconi anemia, complementation group g; FANCGOMIM
3acute myelogenous leukemia;leukemia;Fanconi anaemia GCGP


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