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> Protein (NX_O15320)
Protein (NX_O15320)
Protein
Gene SymbolCTAGE5 to neXtProt (NX_O15320)
DescriptioncTAGE family member 5
Chromosome14
Location14q21.1 (39734488 ~ 39856156) to Ensembl
Sequene Features : Isoforms 10, Variants 104, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of catalytic activity .enzyme activator activity .membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
10 104 13
2014-09-19protein level
10 83 13
2014-05-27protein level
10 83 15
2014-02-25protein level
10 82 12
2013-12-09protein level
10 68 12
2013-11-01protein level
10 65 12
2013-09-12protein level
10 65 12
2013-08-17protein level
10 65 13
2013-07-15protein level
8 52 12
2013-06-11protein level
8 52 12
2013-02-12protein level
8 27 62
2012-12-20protein level
8 28 62
2012-10-30protein level
8 29 62
2012-10-07protein level
8 29 9
2012-08-24protein level
8 28 9
2012-07-28protein level
8 28 9
2012-06-08protein level
8 37 9
2012-05-07protein level
8 34 9
2012-04-10protein level
8 34 9
2012-01-13protein level
8 30 9
2011-12-20protein level
8 30 9
2011-11-11protein level
8 30 8
2011-08-23protein level
8 30 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15320-1
0 22 17 90939.4212
NX_O15320-10
0 21 17 89590.6274
NX_O15320-2
0 19 17 86478.1106
NX_O15320-3
0 21 17 87781.7457
NX_O15320-4
2 19 17 86756.4706
NX_O15320-5
0 23 16 91540.6726
NX_O15320-6
0 21 16 82391.7877
NX_O15320-7
0 18 17 83320.4351
NX_O15320-8
0 20 17 81790.5363
NX_O15320-9
1 17 13 76831.6037
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1050253,EBI-744674 SS18L1  
  .positive regulation of dendrite morphogenesis
.positive regulation of transcription, DNA-templated
.chromatin modification
  + 2 more...
.N/A .nBAF complex
.nuclear body
.nucleus
  + 3 more...
2 EBI-1050253,EBI-348380 PSMA3  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.proteasome core complex
  + 5 more...
3 EBI-1050253,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
4 EBI-1050253,EBI-10182647 TTC23L  
  .response to endoplasmic reticulum stress .N/A .N/A
5 EBI-1050253,EBI-308614 CEP57  
  .protein homooligomerization
.microtubule anchoring
.fibroblast growth factor receptor signaling pathway
  + 5 more...
.protein homodimerization activity
.fibroblast growth factor binding
.microtubule cytoskeleton
.microtubule
.cytosol
  + 5 more...
6 EBI-1050253,EBI-10175300 CCHCR1  
  .cell differentiation
.multicellular organismal development
.protein export from nucleus
.N/A .centriole
.cytoplasm
.nucleus
7 EBI-1050253,EBI-741835 MAGEB18  
  .N/A .N/A .cytoplasm
8 EBI-1050253,EBI-359444 RASAL2  
  .negative regulation of Ras protein signal transduction
.positive regulation of GTPase activity
.signal transduction
.GTPase activator activity .intrinsic component of the cytoplasmic side of the plasma membrane
.cytoplasm
9 EBI-1050253,EBI-744586 EMILIN1  
  .extracellular matrix organization
.positive regulation of cell-substrate adhesion
.cell adhesion
.extracellular matrix constituent conferring elasticity .extracellular exosome
.extracellular matrix
.collagen trimer
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland121
ascites25
bladder33
blood106
bone41
bone marrow20
brain10
cervix41
connective tissue26
embryonic tissue4
esophagus49
eye4
heart33
intestine8
kidney4
liver141
lung5
lymph22
lymph node55
mammary gland19
mouth15
muscle47
ovary29
pancreas37
pharynx24
pituitary gland60
placenta28
prostate5
skin4
stomach83
testis2
thymus25
thyroid42
tonsil58
trachea77
uterus68
vascular19
Health State
TissuesTPM*
normal1
adrenal tumor237
breast (mammary gland) tumor21
cervical tumor57
chondrosarcoma48
colorectal tumor53
esophageal tumor57
gastrointestinal tumor84
germ cell tumor7
head and neck tumor7
kidney tumor14
leukemia190
liver tumor208
lung tumor19
lymphoma13
non-neoplasia41
ovarian tumor26
pancreatic tumor28
primitive neuroectodermal tumor of the CNS31
prostate cancer19
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor110
Developmental Stage
TissuesTPM*
adult36
embryoid body28
blastocyst16
fetus1
juvenile251
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.1
adrenal gland22.7
appendix13.6
bone marrow10.8
cerebral cortex7.4
colon22.5
duodenum40.8
esophagus18.6
gallbladder22.9
heart muscle10.5
kidney37.6
liver41.3
lung11.7
lymph node13.1
ovary7.7
pancreas16.2
placenta8.2
prostate17.7
salivary gland31.6
skin6.7
small intestine39.5
spleen11.9
stomach27
testis16.8
thyroid gland38.5
urinary bladder14.6
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastLow
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineLow
colonMedium
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusLow
fallopian tubeMedium
gallbladderHigh
hippocampusHigh
kidneyMedium
lateral ventricleMedium
liverMedium
lungHigh
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasHigh
parathyroid glandLow
placentaLow
prostateMedium
rectumLow
salivary glandHigh
seminal vesicleMedium
skin 1Low
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 2Low
spleenLow
stomach 1High
stomach 2High
testisMedium
thyroid glandHigh
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602132, gene) Cutaneous t-cell lymphoma-associated antigen 5; CTAGE5OMIM


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