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> Protein (NX_O15327)
Protein (NX_O15327)
Protein
Gene SymbolINPP4B to neXtProt (NX_O15327)
DescriptionType II inositol 3,4-bisphosphate 4-phosphatase
Chromosome4
Location4q31.21 (142944313 ~ 143768585) to Ensembl
Sequene Features : Isoforms 2, Variants 130, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of protein kinase B signaling
.regulation of bone remodeling
.regulation of nucleocytoplasmic transport
  + 8 more...
.phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
.phosphatidylinositol trisphosphate phosphatase activity
.phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity
.lipid binding
.cytosol
.Golgi apparatus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 130 0
2014-09-19protein level
2 109 0
2014-05-27protein level
2 109 0
2014-02-25protein level
2 108 0
2013-12-09protein level
2 87 0
2013-11-01protein level
2 84 0
2013-09-12protein level
2 84 1
2013-08-17protein level
1 84 1
2013-07-15protein level
1 63 1
2013-06-11protein level
1 63 1
2013-02-12protein level
1 19 1
2012-12-20protein level
1 20 1
2012-10-30protein level
1 28 1
2012-10-07protein level
1 28 1
2012-08-24protein level
1 18 1
2012-07-28protein level
1 18 1
2012-06-08protein level
1 20 1
2012-05-07protein level
1 20 1
2012-04-10protein level
1 20 1
2012-01-13protein level
1 13 1
2011-12-20protein level
1 13 1
2011-11-11protein level
1 13 1
2011-08-23transcript level
1 13 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15327-1
40 5 0 104671.1681
NX_O15327-2
1 5 0 14730.4106
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder66
bone41
bone marrow20
brain21
connective tissue46
esophagus49
heart11
intestine17
kidney23
liver9
lung26
lymph node33
mammary gland112
muscle28
nerve64
pancreas18
prostate10
skin80
stomach41
testis32
trachea57
umbilical cord72
uterus25
vascular19
Health State
TissuesTPM*
normal18
bladder carcinoma227
breast (mammary gland) tumor139
chondrosarcoma84
colorectal tumor17
esophageal tumor57
gastrointestinal tumor33
germ cell tumor18
lymphoma13
pancreatic tumor38
skin tumor87
soft tissue/muscle tissue tumor23
Developmental Stage
TissuesTPM*
adult25
neonate32
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.7
adrenal gland4.9
appendix7.5
bone marrow1.5
cerebral cortex4.2
colon7.2
duodenum4.9
esophagus8.6
gallbladder10.1
heart muscle17.2
kidney4.8
liver1.8
lung5.5
lymph node12.4
ovary6.7
pancreas1.5
placenta5.3
prostate5
salivary gland1.4
skin3
small intestine5.9
spleen5.8
stomach6.6
testis37.5
thyroid gland5.4
urinary bladder16.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607494, gene) Inositol polyphosphate-4-phosphatase, type ii, 105-kd; INPP4BOMIM


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