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> Protein (NX_O15405)
Protein (NX_O15405)
Protein
Gene SymbolTOX3 to neXtProt (NX_O15405)
DescriptionTOX high mobility group box family member 3
Chromosome16
Location16q12.1 (52471917 ~ 52581714) to Ensembl
Sequene Features : Isoforms 2, Variants 64, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of transcription, DNA-templated
.negative regulation of neuron apoptotic process
.apoptotic process
  + 2 more...
.phosphoprotein binding
.protein homodimerization activity
.estrogen response element binding
.chromatin binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 64 0
2014-09-19protein level
2 55 0
2014-05-27protein level
2 55 0
2014-02-25protein level
2 55 0
2013-12-09protein level
2 47 0
2013-11-01protein level
2 47 0
2013-09-12protein level
2 47 0
2013-08-17protein level
2 47 0
2013-07-15protein level
2 23 0
2013-06-11protein level
2 23 0
2013-02-12protein level
2 9 0
2012-12-20protein level
2 13 0
2012-10-30protein level
2 15 0
2012-10-07protein level
2 15 0
2012-08-24protein level
2 13 0
2012-07-28protein level
2 13 0
2012-06-08protein level
2 13 0
2012-05-07protein level
2 13 0
2012-04-10protein level
2 13 0
2012-01-13protein level
1 9 0
2011-12-20protein level
1 9 0
2011-11-11protein level
1 9 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15405-1
2 11 3 63302.2639
NX_O15405-2
2 11 3 63060.4058
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain10
ear124
embryonic tissue23
intestine47
kidney37
liver9
lung2
mammary gland52
muscle9
nerve64
ovary19
pancreas51
prostate5
stomach62
testis13
uterus4
Health State
TissuesTPM*
normal14
breast (mammary gland) tumor21
gastrointestinal tumor25
germ cell tumor26
glioma9
leukemia10
ovarian tumor26
pancreatic tumor38
prostate cancer9
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult12
embryoid body14
blastocyst32
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland2.9
appendix1.7
cerebral cortex5.2
colon12.5
duodenum9.1
gallbladder6.3
kidney9.3
liver3
pancreas1.5
prostate2.3
salivary gland2.2
small intestine8.3
stomach17.7
urinary bladder8.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611416, gene) Tox high mobility group box family member 3; TOX3OMIM


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