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> Protein (NX_O15481)
Protein (NX_O15481)
Protein
Gene SymbolMAGEB4 to neXtProt (NX_O15481)
DescriptionMelanoma-associated antigen B4
ChromosomeX
LocationXp21.2 (30260057 ~ 30262293) to Ensembl
Sequene Features : Isoforms 1, Variants 82, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 82 0
2014-09-19protein level
1 63 0
2014-05-27protein level
1 63 1
2014-02-25protein level
1 63 1
2013-12-09protein level
1 58 1
2013-11-01protein level
1 56 1
2013-09-12protein level
1 56 1
2013-08-17protein level
1 56 1
2013-07-15protein level
1 39 1
2013-06-11protein level
1 39 1
2013-02-12protein level
1 19 1
2012-12-20protein level
1 19 1
2012-10-30protein level
1 20 1
2012-10-07protein level
1 20 1
2012-08-24protein level
1 19 1
2012-07-28protein level
1 19 1
2012-06-08protein level
1 14 1
2012-05-07protein level
1 14 1
2012-04-10protein level
1 14 1
2012-01-13protein level
1 5 1
2011-12-20protein level
1 5 1
2011-11-11protein level
1 5 1
2011-08-23protein level
1 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15481-1
16 0 2 38898.6662
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751857,EBI-740220 HGS  
  .positive regulation of exosomal secretion
.protein localization to membrane
.membrane organization
  + 13 more...
.metal ion binding
.protein domain specific binding
.extracellular exosome
.intracellular membrane-bounded organelle
.multivesicular body membrane
  + 6 more...
2 EBI-751857,EBI-714790 WDR62  
  .neurogenesis
.cerebral cortex development
.N/A .cytoplasm
.nucleoplasm
.nucleus
.spindle pole
3 EBI-751857,EBI-1047263 KRT38  
  .N/A .structural molecule activity .extracellular exosome
.intermediate filament
4 EBI-751857,EBI-10182930 MAGEA8  
  .N/A .N/A .N/A
5 EBI-751857,EBI-876651 ROCK1  
  .regulation of cell motility
.regulation of establishment of cell polarity
.positive regulation of focal adhesion assembly
  + 27 more...
.metal ion binding
.ATP binding
.protein serine/threonine kinase activity
.protein kinase activity
.bleb
.lamellipodium
.plasma membrane
  + 5 more...
6 EBI-751857,EBI-394678 MED21  
  .positive regulation of transcription from RNA polymerase II promoter
.stem cell maintenance
.regulation of transcription from RNA polymerase II promoter
  + 2 more...
.DNA-directed RNA polymerase activity
.transcription coactivator activity
.mediator complex
7 EBI-751857,EBI-747225 RUNDC3A  
  .small GTPase mediated signal transduction .GTPase regulator activity
.guanylate cyclase activator activity
.plasma membrane
.cytosol
8 EBI-751857,EBI-2556193 KANK2  
  .negative regulation of G1/S transition of mitotic cell cycle
.negative regulation of vitamin D receptor signaling pathway
.negative regulation of programmed cell death
  + 5 more...
.N/A .mitochondrion
.cytoplasm
9 EBI-751857,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
10 EBI-751857,EBI-10171416 CCDC136  
  .N/A .N/A .integral component of membrane
.mitochondrion
11 EBI-751857,EBI-10183007 FERD3L  
  .regulation of neurogenesis
.cell development
.negative regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .nucleus
12 EBI-751857,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
13 EBI-751857,EBI-9089622 ZNF341  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
14 EBI-751857,EBI-2513462 USP25  
  .protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.regulation of proteasomal protein catabolic process
  + 3 more...
.SUMO binding
.peptidase activity
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
testis41
Health State
TissuesTPM*
normal4
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis10
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300153, gene) Melanoma antigen, family b, 4; MAGEB4OMIM


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