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> Protein (NX_O15503)
Protein (NX_O15503)
Protein
Gene SymbolINSIG1 to neXtProt (NX_O15503)
DescriptionInsulin-induced gene 1 protein
Chromosome7
Location7q36.2 (155089486 ~ 155101945) to Ensembl
Sequene Features : Isoforms 2, Variants 35, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of cargo loading into COPII-coated vesicle
.cranial suture morphogenesis
.palate development
  + 11 more...
.N/A .SREBP-SCAP-Insig complex
.endoplasmic reticulum membrane
.endoplasmic reticulum
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 35 4
2014-09-19protein level
2 24 4
2014-05-27protein level
2 21 4
2014-02-25protein level
2 21 4
2013-12-09protein level
2 12 4
2013-11-01protein level
2 12 4
2013-09-12protein level
2 12 4
2013-08-17protein level
2 12 4
2013-07-15protein level
2 11 2
2013-06-11protein level
2 11 2
2013-02-12protein level
2 4 2
2012-12-20protein level
1 3 2
2012-10-30protein level
1 6 2
2012-10-07protein level
1 6 2
2012-08-24protein level
1 6 2
2012-07-28protein level
1 6 2
2012-06-08protein level
1 12 2
2012-05-07protein level
1 11 2
2012-04-10protein level
1 11 2
2012-01-13protein level
1 13 2
2011-12-20protein level
1 13 2
2011-11-11protein level
1 13 2
2011-08-23protein level
1 13 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15503-1
6 5 0 29967.363
NX_O15503-2
1 5 0 17518.9127
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland121
ascites100
bladder167
blood278
bone69
bone marrow102
brain103
cervix41
connective tissue87
ear248
embryonic tissue23
eye114
heart78
intestine94
kidney99
liver292
lung92
lymph383
lymph node111
mammary gland257
mouth90
muscle9
nerve128
ovary39
pancreas37
parathyroid48
pituitary gland484
placenta123
prostate131
salivary gland197
skin218
spleen56
stomach62
testis264
thymus138
tonsil58
trachea57
uterus60
vascular77
Health State
TissuesTPM*
normal114
adrenal tumor79
breast (mammary gland) tumor139
chondrosarcoma96
colorectal tumor97
gastrointestinal tumor92
germ cell tumor174
glioma27
head and neck tumor67
kidney tumor232
leukemia105
liver tumor124
lung tumor48
lymphoma332
non-neoplasia93
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS118
prostate cancer202
retinoblastoma215
skin tumor207
soft tissue/muscle tissue tumor39
uterine tumor55
Developmental Stage
TissuesTPM*
adult119
embryoid body42
blastocyst16
neonate32
fetus120
infant42
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue61.4
adrenal gland23
appendix33.5
bone marrow27.2
cerebral cortex36.8
colon30.1
duodenum44.4
esophagus23
gallbladder33.3
heart muscle14.6
kidney15.6
liver210.6
lung40.3
lymph node28.8
ovary14.2
pancreas49.3
placenta50.8
prostate61.4
salivary gland48.8
skin7.6
small intestine30.3
spleen16.7
stomach38.6
testis35.3
thyroid gland12.3
urinary bladder23.6
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*602055, gene) Insulin-induced gene 1; INSIG1OMIM


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