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> Protein (NX_O15516)
Protein (NX_O15516)
Protein
Gene SymbolCLOCK to neXtProt (NX_O15516)
DescriptionCircadian locomoter output cycles protein kaput
Chromosome4
Location4q12 (56294070 ~ 56413305) to Ensembl
Sequene Features : Isoforms 1, Variants 84, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of glucocorticoid receptor signaling pathway
.regulation of type B pancreatic cell development
.cellular response to ionizing radiation
  + 19 more...
.E-box binding
.sequence-specific DNA binding
.chromatin DNA binding
  + 9 more...
.intracellular membrane-bounded organelle
.chromatoid body
.chromosome
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 84 8
2014-09-19protein level
1 68 8
2014-05-27protein level
1 68 8
2014-02-25protein level
1 67 1
2013-12-09protein level
1 55 1
2013-11-01protein level
1 53 1
2013-09-12protein level
1 53 1
2013-08-17protein level
1 53 1
2013-07-15protein level
1 43 1
2013-06-11protein level
1 43 1
2013-02-12protein level
1 26 2
2012-12-20protein level
1 25 2
2012-10-30protein level
1 29 2
2012-10-07protein level
1 29 2
2012-08-24protein level
1 16 2
2012-07-28protein level
1 16 2
2012-06-08protein level
1 23 2
2012-05-07protein level
1 23 2
2012-04-10protein level
1 23 2
2012-01-13protein level
1 15 2
2011-12-20protein level
1 15 2
2011-11-11protein level
1 15 2
2011-08-23protein level
1 15 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15516-1
29 0 1 95243.8954
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland60
ascites25
bladder33
bone41
bone marrow20
brain21
connective tissue40
embryonic tissue28
eye47
heart44
intestine30
kidney52
liver34
lung38
lymph node44
mammary gland33
mouth30
muscle150
nerve64
ovary78
pancreas60
parathyroid242
pharynx24
pituitary gland60
placenta49
prostate110
skin66
spleen37
testis39
thymus12
thyroid21
tonsil58
trachea19
uterus47
vascular96
Health State
TissuesTPM*
normal53
breast (mammary gland) tumor21
chondrosarcoma36
colorectal tumor35
gastrointestinal tumor8
germ cell tumor22
glioma55
head and neck tumor14
kidney tumor14
liver tumor20
non-neoplasia10
ovarian tumor105
pancreatic tumor19
primitive neuroectodermal tumor of the CNS23
prostate cancer67
skin tumor55
soft tissue/muscle tissue tumor55
uterine tumor55
Developmental Stage
TissuesTPM*
adult47
embryoid body42
blastocyst16
fetus62
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.3
adrenal gland7.7
appendix5.4
bone marrow1.5
cerebral cortex9.6
colon7.9
duodenum5.9
esophagus13.2
gallbladder6.8
heart muscle8.3
kidney8.3
liver3.6
lung5.5
lymph node3.6
ovary8.1
pancreas3.3
placenta6.4
prostate7.8
salivary gland3.9
skin6.1
small intestine7.3
spleen5.8
stomach7.8
testis21.5
thyroid gland13.3
urinary bladder6
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasLow
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineLow
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Low
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*601851, gene) Circadian locomotor output cycles kaput; CLOCKOMIM


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