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> Protein (NX_O15551)
Protein (NX_O15551)
Protein
Gene SymbolCLDN3 to neXtProt (NX_O15551)
DescriptionClaudin-3
Chromosome7
Location7q11.23 (73183328 ~ 73184600) to Ensembl
Sequene Features : Isoforms 1, Variants 16, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
.signal transduction
.epithelial cell morphogenesis
.response to hypoxia
.structural molecule activity
.transmembrane signaling receptor activity
.extracellular exosome
.lateral plasma membrane
.integral component of membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 16 1
2014-09-19protein level
1 12 1
2014-05-27protein level
1 12 1
2014-02-25protein level
1 12 1
2013-12-09protein level
1 8 1
2013-11-01protein level
1 7 1
2013-09-12protein level
1 7 1
2013-08-17protein level
1 7 1
2013-07-15protein level
1 7 1
2013-06-11protein level
1 7 1
2013-02-12protein level
1 4 3
2012-12-20protein level
1 4 3
2012-10-30protein level
1 5 3
2012-10-07protein level
1 5 3
2012-08-24protein level
1 5 3
2012-07-28protein level
1 5 3
2012-06-08protein level
1 5 3
2012-05-07protein level
1 5 3
2012-04-10protein level
1 5 3
2012-01-13protein level
1 4 3
2011-12-20protein level
1 4 3
2011-11-11protein level
1 4 3
2011-08-23protein level
1 4 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O15551-1
7 0 1 23303.0693
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites75
cervix82
connective tissue6
embryonic tissue14
eye19
heart11
intestine823
kidney137
liver9
lung44
lymph node55
mammary gland72
ovary206
pancreas388
parathyroid97
prostate89
salivary gland98
stomach62
testis4
thymus12
thyroid236
trachea19
uterus47
Health State
TissuesTPM*
normal53
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma12
colorectal tumor88
gastrointestinal tumor109
germ cell tumor11
kidney tumor29
liver tumor20
lung tumor19
non-neoplasia72
ovarian tumor262
pancreatic tumor38
prostate cancer67
uterine tumor88
Developmental Stage
TissuesTPM*
adult97
embryoid body14
fetus37
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix5.2
colon95.3
duodenum32.7
gallbladder2.2
kidney9.5
liver6
lung3.9
pancreas12
prostate35.2
salivary gland24.4
small intestine63
stomach1.1
thyroid gland7
Tissues
TissuesExpression level
adrenal glandLow
appendixHigh
breastMedium
bronchusHigh
cervix, uterineLow
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
fallopian tubeHigh
gallbladderHigh
kidneyHigh
liverHigh
lungLow
nasopharynxHigh
pancreasHigh
parathyroid glandMedium
placentaMedium
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skin 1Low
skin 2Medium
small intestineHigh
stomach 1High
stomach 2High
testisMedium
thyroid glandHigh
tonsilLow
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602910, gene) Claudin 3; CLDN3OMIM


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