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> Protein (NX_O43143)
Protein (NX_O43143)
Protein
Gene SymbolDHX15 to neXtProt (NX_O43143)
DescriptionPutative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15
Chromosome4
Location4p15.2 (24519064 ~ 24586173) to Ensembl
Sequene Features : Isoforms 1, Variants 72, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.RNA splicing
.mRNA processing
.mRNA splicing, via spliceosome
.poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
  + 2 more...
.cytoplasm
.nucleolus
.U12-type spliceosomal complex
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 72 9
2014-09-19protein level
1 51 9
2014-05-27protein level
1 51 9
2014-02-25protein level
1 50 10
2013-12-09protein level
1 47 10
2013-11-01protein level
1 41 8
2013-09-12protein level
1 41 8
2013-08-17protein level
1 41 8
2013-07-15protein level
1 26 3
2013-06-11protein level
1 26 3
2013-02-12protein level
1 9 4
2012-12-20protein level
1 9 4
2012-10-30protein level
1 10 4
2012-10-07protein level
1 10 4
2012-08-24protein level
1 3 4
2012-07-28protein level
1 3 4
2012-06-08protein level
1 7 4
2012-05-07protein level
1 7 4
2012-04-10protein level
1 7 4
2012-01-13protein level
1 9 4
2011-12-20protein level
1 9 4
2011-11-11protein level
1 9 4
2011-08-23protein level
1 9 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43143-1
36 0 1 90874.9054
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1237044,EBI-714003 RBM5  
  .positive regulation of apoptotic process
.gene expression
.RNA splicing
  + 6 more...
.poly(A) RNA binding
.zinc ion binding
.mRNA binding
  + 3 more...
.spliceosomal complex
.nucleoplasm
.nucleus
2 EBI-1237044,EBI-721525 RBM10  
  .RNA splicing
.mRNA processing
.poly(A) RNA binding
.identical protein binding
.protein complex binding
  + 2 more...
.nucleoplasm
.nucleus
3 EBI-1237044,EBI-2462271 SF3A2  
  .gene expression
.RNA splicing
.mRNA processing
  + 2 more...
.poly(A) RNA binding
.zinc ion binding
.catalytic step 2 spliceosome
.small nuclear ribonucleoprotein complex
.spliceosomal complex
.nucleoplasm
4 EBI-1237044,EBI-2691671 SUGP1  
  .gene expression
.RNA splicing
.mRNA splicing, via spliceosome
.poly(A) RNA binding .spliceosomal complex
.nucleoplasm
5 EBI-1237044,EBI-3439227 ZGPAT  
  .negative regulation of transcription, DNA-templated
.negative regulation of epidermal growth factor-activated receptor activity
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.nucleus
6 EBI-1237044,EBI-740272 RBM17  
  .alternative mRNA splicing, via spliceosome .RNA binding
.nucleotide binding
.spliceosomal complex
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland151
ascites50
bladder200
blood114
bone139
bone marrow41
brain107
cervix41
connective tissue147
ear683
embryonic tissue155
esophagus99
eye124
heart156
intestine120
kidney180
liver87
lung137
lymph22
lymph node111
mammary gland165
mouth317
muscle103
nerve193
ovary88
pancreas60
parathyroid97
pharynx98
pituitary gland121
placenta67
prostate84
salivary gland49
skin85
spleen93
stomach114
testis128
thymus665
thyroid21
tonsil176
trachea115
umbilical cord145
uterus103
vascular154
Health State
TissuesTPM*
normal116
adrenal tumor79
bladder carcinoma170
breast (mammary gland) tumor150
cervical tumor57
chondrosarcoma144
colorectal tumor106
esophageal tumor115
gastrointestinal tumor101
germ cell tumor246
glioma9
head and neck tumor171
kidney tumor72
leukemia31
liver tumor156
lung tumor116
lymphoma69
non-neoplasia93
ovarian tumor105
pancreatic tumor38
primitive neuroectodermal tumor of the CNS55
prostate cancer105
retinoblastoma301
skin tumor95
soft tissue/muscle tissue tumor87
uterine tumor77
Developmental Stage
TissuesTPM*
adult116
embryoid body100
blastocyst276
neonate193
fetus199
infant85
juvenile233
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue52.6
adrenal gland51.4
appendix79.6
bone marrow141.7
cerebral cortex38.5
colon68.3
duodenum52.6
esophagus60.6
gallbladder57.8
heart muscle33.9
kidney48.7
liver31.2
lung56.7
lymph node87.4
ovary61.2
pancreas35.7
placenta68.3
prostate57.1
salivary gland34
skin69.3
small intestine56.2
spleen61.8
stomach62
testis49.2
thyroid gland54.8
urinary bladder65.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603403, gene) Deah box polypeptide 15; DHX15OMIM


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