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> Protein (NX_O43148)
Protein (NX_O43148)
Protein
Gene SymbolRNMT to neXtProt (NX_O43148)
DescriptionmRNA cap guanine-N7 methyltransferase
Chromosome18
Location18p11.21 (13726659 ~ 13764557) to Ensembl
Sequene Features : Isoforms 2, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.RNA (guanine-N7)-methylation
.viral process
.gene expression
  + 2 more...
.mRNA (guanine-N7-)-methyltransferase activity
.RNA binding
.receptor complex
.mRNA cap binding complex
.nucleolus
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 65 6
2014-09-19protein level
2 48 6
2014-05-27protein level
2 48 6
2014-02-25protein level
2 48 6
2013-12-09protein level
2 36 6
2013-11-01protein level
2 32 6
2013-09-12protein level
2 32 6
2013-08-17protein level
2 32 6
2013-07-15protein level
2 22 4
2013-06-11protein level
2 22 4
2013-02-12protein level
2 12 6
2012-12-20protein level
2 16 6
2012-10-30protein level
2 20 6
2012-10-07protein level
2 20 4
2012-08-24protein level
2 19 4
2012-07-28protein level
2 19 4
2012-06-08protein level
2 9 4
2012-05-07protein level
2 9 4
2012-04-10protein level
2 9 4
2012-01-13protein level
2 9 4
2011-12-20protein level
2 9 4
2011-11-11protein level
2 9 2
2011-08-23protein level
2 9 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43148-1
1 20 0 54809.1083
NX_O43148-2
3 20 0 57687.6893
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites150
blood57
bone83
bone marrow41
brain32
cervix103
connective tissue33
embryonic tissue84
esophagus49
eye14
heart33
intestine56
kidney66
liver107
lung41
lymph22
lymph node55
mammary gland105
mouth181
muscle47
nerve64
ovary49
pancreas9
placenta24
prostate26
skin42
testis43
thymus50
thyroid150
trachea38
uterus17
vascular38
Health State
TissuesTPM*
normal46
breast (mammary gland) tumor53
chondrosarcoma60
colorectal tumor53
esophageal tumor57
gastrointestinal tumor67
germ cell tumor45
glioma37
head and neck tumor127
kidney tumor43
leukemia42
liver tumor72
lung tumor19
lymphoma13
non-neoplasia41
ovarian tumor52
pancreatic tumor9
primitive neuroectodermal tumor of the CNS7
prostate cancer19
skin tumor71
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult52
embryoid body85
blastocyst65
fetus52
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.8
adrenal gland8.8
appendix13.1
bone marrow26.5
cerebral cortex17.3
colon9.6
duodenum7.8
esophagus10.8
gallbladder10.5
heart muscle16.4
kidney10.7
liver5.4
lung9.2
lymph node14.6
ovary16.7
pancreas5.1
placenta14.8
prostate11.2
salivary gland9
skin10.7
small intestine8
spleen11
stomach9.6
testis17.2
thyroid gland18.1
urinary bladder13.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603514, gene) Rna guanine-7-methyltransferase; RNMTOMIM


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