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> Protein (NX_O43169)
Protein (NX_O43169)
Protein
Gene SymbolCYB5B to neXtProt (NX_O43169)
DescriptionCytochrome b5 type B
Chromosome16
Location16q22.1 (69458428 ~ 69500169) to Ensembl
Sequene Features : Isoforms 1, Variants 14, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.oxidation-reduction process .metal ion binding
.heme binding
.integral component of membrane
.membrane
.mitochondrial outer membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 14 5
2014-09-19protein level
1 13 5
2014-05-27protein level
1 13 5
2014-02-25protein level
1 13 4
2013-12-09protein level
1 10 4
2013-11-01protein level
1 10 3
2013-09-12protein level
1 10 3
2013-08-17protein level
1 10 3
2013-07-15protein level
1 11 3
2013-06-11protein level
1 11 3
2013-02-12protein level
1 0 3
2012-12-20protein level
1 0 3
2012-10-30protein level
1 2 3
2012-10-07protein level
1 2 3
2012-08-24protein level
1 2 3
2012-07-28protein level
1 2 3
2012-06-08protein level
1 3 3
2012-05-07protein level
1 3 3
2012-04-10protein level
1 3 3
2012-01-13protein level
1 4 3
2011-12-20protein level
1 4 3
2011-11-11protein level
1 4 3
2011-08-23protein level
1 4 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43169-1
6 0 0 16321.9281
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland698
ascites200
bladder167
blood114
bone83
bone marrow61
brain87
cervix247
connective tissue114
embryonic tissue136
esophagus49
eye119
heart22
intestine168
kidney71
liver116
lung65
lymph225
lymph node144
mammary gland66
mouth30
muscle94
nerve128
ovary68
pancreas79
parathyroid97
pharynx196
placenta183
prostate52
skin113
spleen93
stomach188
testis114
thymus50
thyroid107
tonsil58
trachea173
umbilical cord72
uterus112
vascular58
Health State
TissuesTPM*
normal97
adrenal tumor237
bladder carcinoma56
breast (mammary gland) tumor96
cervical tumor260
chondrosarcoma36
colorectal tumor133
esophageal tumor57
gastrointestinal tumor286
germ cell tumor136
glioma55
head and neck tumor52
kidney tumor72
leukemia116
liver tumor156
lung tumor116
lymphoma249
non-neoplasia82
ovarian tumor52
pancreatic tumor161
primitive neuroectodermal tumor of the CNS181
prostate cancer38
retinoblastoma279
skin tumor119
soft tissue/muscle tissue tumor231
uterine tumor88
Developmental Stage
TissuesTPM*
adult95
embryoid body57
blastocyst179
neonate64
fetus71
infant340
juvenile305
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue48.9
adrenal gland271
appendix50.6
bone marrow13.5
cerebral cortex54.4
colon90.5
duodenum62.4
esophagus57
gallbladder46.9
heart muscle47.2
kidney54.9
liver41.4
lung50.1
lymph node63.5
ovary41.7
pancreas20.6
placenta72.9
prostate43.4
salivary gland29.2
skin39.8
small intestine62.5
spleen44.9
stomach47.1
testis40.9
thyroid gland53.8
urinary bladder86.7
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverHigh
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaHigh
ovaryHigh
pancreasMedium
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleHigh
skeletal muscleMedium
skin 1High
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2High
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611964, gene) Cytochrome b5, type b (outer mitochondrial membrane); CYB5BOMIM


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