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> Protein (NX_O43252)
Protein (NX_O43252)
Protein
Gene SymbolPAPSS1 to neXtProt (NX_O43252)
DescriptionBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
Chromosome4
Location4q25 (108511433 ~ 108641608) to Ensembl
Sequene Features : Isoforms 1, Variants 72, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
.3'-phosphoadenosine 5'-phosphosulfate metabolic process
.small molecule metabolic process
  + 5 more...
.nucleotidyltransferase activity
.ATP binding
.sulfate adenylyltransferase (ATP) activity
.adenylylsulfate kinase activity
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 72 5
2014-09-19protein level
1 59 5
2014-05-27protein level
1 59 5
2014-02-25protein level
1 58 3
2013-12-09protein level
1 45 3
2013-11-01protein level
1 39 2
2013-09-12protein level
1 39 2
2013-08-17protein level
1 39 2
2013-07-15protein level
1 23 1
2013-06-11protein level
1 23 1
2013-02-12protein level
1 9 1
2012-12-20protein level
1 8 1
2012-10-30protein level
1 10 1
2012-10-07protein level
1 10 1
2012-08-24protein level
1 8 1
2012-07-28protein level
1 8 1
2012-06-08protein level
1 16 1
2012-05-07protein level
1 16 1
2012-04-10protein level
1 16 1
2012-01-13protein level
1 16 1
2011-12-20protein level
1 16 1
2011-11-11protein level
1 16 1
2011-08-23protein level
1 16 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43252-1
30 0 1 70787.4312
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
bladder66
blood163
bone69
bone marrow20
brain172
cervix41
connective tissue120
embryonic tissue117
esophagus99
eye57
heart44
intestine51
kidney90
larynx42
liver14
lung77
lymph45
lymph node55
mammary gland72
mouth45
muscle37
nerve128
ovary78
pancreas28
pharynx245
pituitary gland121
placenta42
prostate47
skin94
spleen56
stomach10
testis32
thymus62
thyroid64
trachea193
uterus168
vascular290
Health State
TissuesTPM*
normal97
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor53
cervical tumor57
chondrosarcoma84
colorectal tumor53
esophageal tumor115
gastrointestinal tumor33
germ cell tumor91
glioma37
head and neck tumor59
kidney tumor130
leukemia127
liver tumor31
lymphoma96
non-neoplasia227
ovarian tumor78
pancreatic tumor28
primitive neuroectodermal tumor of the CNS62
prostate cancer57
retinoblastoma129
skin tumor103
soft tissue/muscle tissue tumor71
uterine tumor166
Developmental Stage
TissuesTPM*
adult72
embryoid body185
blastocyst65
neonate225
fetus96
infant170
juvenile179
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.4
adrenal gland13.5
appendix30.5
bone marrow15.6
cerebral cortex45.9
colon20.8
duodenum13.4
esophagus34.1
gallbladder26.3
heart muscle12.1
kidney26.8
liver5.9
lung38.9
lymph node31.1
ovary26.8
pancreas20.3
placenta15.1
prostate36.6
salivary gland45.1
skin38.7
small intestine14.4
spleen15.7
stomach52.2
testis18.5
thyroid gland19.5
urinary bladder37.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603262, gene) 3-prime-@phosphoadenosine 5-prime-phosphosulfate synthase 1; PAPSS1OMIM


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