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> Protein (NX_O43290)
Protein (NX_O43290)
Protein
Gene SymbolSART1 to neXtProt (NX_O43290)
DescriptionU4/U6.U5 tri-snRNP-associated protein 1
Chromosome11
Location11q13.1 (65729160 ~ 65747299) to Ensembl
Sequene Features : Isoforms 1, Variants 75, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.intrinsic apoptotic signaling pathway
.positive regulation of cytotoxic T cell differentiation
.mRNA cis splicing, via spliceosome
  + 4 more...
.poly(A) RNA binding .catalytic step 2 spliceosome
.U4/U6 x U5 tri-snRNP complex
.Cajal body
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 75 13
2014-09-19protein level
1 61 13
2014-05-27protein level
1 61 13
2014-02-25protein level
1 60 13
2013-12-09protein level
1 39 13
2013-11-01protein level
1 38 12
2013-09-12protein level
1 38 12
2013-08-17protein level
1 38 12
2013-07-15protein level
1 28 11
2013-06-11protein level
1 28 11
2013-02-12protein level
1 16 12
2012-12-20protein level
1 14 12
2012-10-30protein level
1 15 12
2012-10-07protein level
1 15 12
2012-08-24protein level
1 14 12
2012-07-28protein level
1 14 12
2012-06-08protein level
1 16 12
2012-05-07protein level
1 14 12
2012-04-10protein level
1 14 12
2012-01-13protein level
1 14 12
2011-12-20protein level
1 14 12
2011-11-11protein level
1 14 10
2011-08-23protein level
1 14 10
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43290-1
37 0 0 90200.0026
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-607761,EBI-474067 SUMO3  
  .positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.cellular protein metabolic process
.post-translational protein modification
  + 2 more...
.SUMO transferase activity .extracellular exosome
.PML body
.cytoplasm
  + 3 more...
2 EBI-607761,EBI-80140 SUMO1  
  .protein localization to nuclear pore
.regulation of interferon-gamma-mediated signaling pathway
.interferon-gamma-mediated signaling pathway
  + 13 more...
.poly(A) RNA binding
.ubiquitin protein ligase binding
.SUMO transferase activity
.transcription factor binding
.synapse
.nuclear membrane
.dendrite
  + 8 more...
3 EBI-607761,EBI-632715 SNW1  
  .cellular response to retinoic acid
.positive regulation of vitamin D receptor signaling pathway
.regulation of vitamin D receptor signaling pathway
  + 19 more...
.SMAD binding
.poly(A) RNA binding
.retinoic acid receptor binding
  + 5 more...
.catalytic step 2 spliceosome
.nuclear matrix
.spliceosomal complex
  + 3 more...
4 EBI-607761,EBI-607755 UBL5  
  .positive regulation of protein targeting to mitochondrion
.cellular protein modification process
.mRNA splicing, via spliceosome
.protein tag .cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland91
ascites100
bladder66
blood98
bone125
bone marrow41
brain67
cervix103
connective tissue40
embryonic tissue70
esophagus49
eye95
heart67
intestine112
kidney52
larynx170
liver136
lung38
lymph112
lymph node33
mammary gland119
mouth90
muscle56
ovary59
pancreas112
placenta74
prostate31
salivary gland98
skin71
spleen74
stomach52
testis20
thymus50
thyroid107
trachea38
umbilical cord72
uterus51
vascular116
Health State
TissuesTPM*
normal55
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor118
cervical tumor115
chondrosarcoma108
colorectal tumor79
esophageal tumor57
gastrointestinal tumor101
germ cell tumor83
glioma74
head and neck tumor119
kidney tumor72
leukemia74
liver tumor270
lung tumor58
lymphoma166
non-neoplasia10
ovarian tumor52
pancreatic tumor190
primitive neuroectodermal tumor of the CNS141
prostate cancer28
retinoblastoma129
skin tumor87
soft tissue/muscle tissue tumor63
uterine tumor33
Developmental Stage
TissuesTPM*
adult75
embryoid body57
blastocyst65
neonate128
fetus64
infant42
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.7
adrenal gland19.4
appendix26.2
bone marrow40.3
cerebral cortex22.1
colon16
duodenum18.3
esophagus12.9
gallbladder10.7
heart muscle15.6
kidney16.9
liver13.5
lung24
lymph node25.5
ovary20.9
pancreas13.1
placenta21.6
prostate20.7
salivary gland18.2
skin22.3
small intestine19.8
spleen37.2
stomach19.9
testis23.8
thyroid gland12.4
urinary bladder10.8
Tissues
TissuesExpression level
adrenal glandLow
appendixMedium
breastMedium
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonLow
duodenumMedium
epididymisMedium
esophagusHigh
gallbladderMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
nasopharynxHigh
oral mucosaHigh
pancreasMedium
placentaHigh
rectumMedium
skin 1High
skin 2Low
small intestineLow
stomach 1High
stomach 2Medium
testisMedium
tonsilLow
urinary bladderLow
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605941, gene) Squamous cell carcinoma antigen recognized by t cells 1; SART1OMIM


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